Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.65 |
| ▸ | PPARG | P37231 | 16/20 | 0.65 |
| ▸ | PPARD | Q03181 | 8/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5106308 | 0.98 | PPARA (0.63) | PPARAPPARGPPARD | |
| SCHEMBL6700058 | 0.91 | PPARA (0.78) | PPARAPPARGPPARD | |
| SCHEMBL6699850 | 0.89 | PPARA (0.81) | PPARAPPARGPPARD | |
| SCHEMBL5103297 | 0.89 | PPARA (0.77) | PPARAPPARGPPARD | |
| SCHEMBL5105696 | 0.87 | PPARA (0.81) | PPARAPPARGPPARD | |
| SCHEMBL6991817 | 0.84 | PPARA (0.86) | PPARAPPARGPPARD | |
| SCHEMBL5105881 | 0.83 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL6700443 | 0.83 | PPARA (0.68) | PPARAPPARGPPARD | |
| SCHEMBL6702560 | 0.83 | PPARA (0.71) | PPARAPPARGPPARD | |
| SCHEMBL5111844 | 0.83 | PPARA (0.71) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610696-B2 | Such as 2-(4-(2-(2-(4-(3,5-dimethyl-isoxazol-4-yl)-phenyl)-5-methyloxazol-4-yl) -ethyoxy)-phenoxy)-2-methylpropionic acid for treatment of diabetes (lowering serum triglycerides) | ELI LILLY AND COMPANY | 2003-08-26 | — | — | US | disclosed |
| US-6417212-B1 | PHENYLOXAZOLE SUBSTITUTED ON BENZENEOXYPROPIONIC ACID OR ESTERS | ELI LILLY & COMPANY | 2002-07-09 | — | — | US | disclosed |