Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.55 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.44 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7195803 | 0.97 | ACHE (0.55) | ACHETAAR1MAOBIDO1AGXT | |
| Bromide SCHEMBL7200811 | 0.97 | ACHE (0.55) | ACHETAAR1MAOBIDO1AGXT | |
| Phosphoric Acid SCHEMBL7197782 | 0.90 | ACHE (0.47) | ACHETAAR1MAOBIDO1AGXT | |
| Acetic Acid SCHEMBL8750057 | 0.89 | ACHE (0.46) | ACHETAAR1MAOBHSD17B2 | |
| Iodide SCHEMBL7197885 | 0.88 | TAAR1 (0.53) | ACHETAAR1MAOBIDO1AGXT | |
| Iodide SCHEMBL7197829 | 0.88 | MAPT (0.47) | ACHEMAOB | |
| Acetic Acid SCHEMBL7199841 | 0.87 | CYP1A2 (0.44) | ACHETAAR1MAOBHSD17B2 | |
| Succinic Acid SCHEMBL7199837 | 0.87 | HSD17B2 (0.46) | ACHETAAR1MAOBHSD17B2 | |
| SCHEMBL31208272 | 0.85 | TAAR1 (0.57) | TAAR1MAOBIDO1AGXTCHRM2 | |
| Phosphoric Acid SCHEMBL9318089 | 0.85 | MAOB (0.42) | ACHETAAR1MAOBIDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624173-B2 | PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS | DOW CHEMICAL CO (US) | 2003-04-09 | — | — | EP | disclosed |
| EP-0624173-B1 | PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS | DOW CHEMICAL CO (US) | 1997-04-02 | — | — | EP | disclosed |
| EP-0624173-A1 | PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS. | DOW CHEMICAL CO (US) | 1994-11-17 | — | — | EP | disclosed |
| US-5360886-A | Alklyphenylphosphine or phosphonium catalyst | THE DOW CHEMICAL COMPANY (US) | 1994-11-01 | — | — | US | disclosed |
| US-5310853-A | Epoxy resins | THE DOW CHEMICAL COMPANY (US) | 1994-05-10 | — | — | US | disclosed |
| WO-1993015126-A1 | PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS | THE DOW CHEMICAL COMPANY (US) | 1993-08-05 | — | — | WO | disclosed |
| US-5202407-A | Phosphonium or phosphine catalyst having at least three alkylphenyl groups attached to phosphorus atom | THE DOW CHEMICAL COMPANY (US) | 1993-04-13 | — | — | US | disclosed |