Carbamic Acid

Carbamic Acid

SCHEMBL7201596

N#CCCNP(O)O.NC(=O)O

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
MCL1 Q07820 1/20 0.34
SLC1A2 P43004 1/20 0.32
MAPT P10636 1/20 0.31
PLAU P00749 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40958 0.87
SCHEMBL30148034 0.73 GAA (0.33)
SCHEMBL8558689 0.73
SCHEMBL991911 0.73
SCHEMBL3967703 0.69
Carbamic Acid SCHEMBL28684032 0.67
SCHEMBL462879 0.66
Carbamic Acid SCHEMBL28959944 0.66 KMT2A (0.43) MEN1KMT2AMCL1SLC1A2MAPT
SCHEMBL3725568 0.65
Acetic Acid SCHEMBL9547280 0.64 MAOA (0.41) MEN1KMT2AMCL1SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6605708-B1 Stability HYBRIDON, INC. 2003-08-12 US disclosed
EP-0711302-B1 BUILDING BLOCKS WITH CARBAMATE INTERNUCLEOSIDE LINKAGES AND NOVEL OLIGONUCLEOTIDES DERIVED THEREFROM HYBRIDON INC (US) 1996-10-23 EP disclosed
EP-0711302-A1 BUILDING BLOCKS WITH CARBAMATE INTERNUCLEOSIDE LINKAGES AND NOVEL OLIGONUCLEOTIDES DERIVED THEREFROM HYBRIDON INC (US) 1996-05-15 EP disclosed
WO-1995004066-A1 BUILDING BLOCKS WITH CARBAMATE INTERNUCLEOSIDE LINKAGES AND NOVEL OLIGONUCLEOTIDES DERIVED THEREFROM HYBRIDON, INC. (US) 1995-02-09 WO disclosed