Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.74 |
| ▸ | PPARG | P37231 | 7/20 | 0.74 |
| ▸ | PPARD | Q03181 | 7/20 | 0.74 |
| ▸ | PPARA | Q07869 | 7/20 | 0.74 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.74 |
| ▸ | TSHR | P16473 | 5/20 | 0.74 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.74 |
| ▸ | FABP4 | P15090 | 3/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | TLR2 | O60603 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.74 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.74 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | ESR1 | P03372 | 1/20 | 0.74 |
| ▸ | PDE4A | P27815 | 1/20 | 0.74 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743610 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL14166454 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL11477071 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL16539035 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL8865709 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL15593804 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL7749100 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL2229369 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL23891 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL9106361 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0327523-B1 | NOVEL FATTY ACID ANALOG ENZYME SUBSTRATES | WASHINGTON UNIVERSITY (US) | 1992-06-17 | — | — | EP | claimed |
| EP-0327523-A1 | Novel fatty acid analog enzyme substrates | WASHINGTON UNIVERSITY (US) | 1989-08-09 | — | — | EP | claimed |
| US-6602861-B1 | Acylated phospholipid drugs | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2003-08-05 | — | — | US | disclosed |
| US-5981580-A | IN WHICH THE CARBOXY-TERMINUS HAS BEEN MODIFIED TO FORM VARIOUS AMIDES, ESTERS, KETONES, ALCOHOLS, ALCOHOL ESTERS AND NITRITES THEREOF, AND ARE USEFUL AS SUBSTRATES FOR N-MYRISTOYLTRANSFERASE (NMT) AND/OR ITS ACYL COENZYME | G. D. SEARLE & CO. (US) | 1999-11-09 | — | — | US | disclosed |
| WO-1999050229-A1 | FATTY ACID ANALOGS AND PRODRUGS | G.D. SEARLE & CO. (US) | 1999-10-07 | — | — | WO | disclosed |
| US-5959145-A | 12-(METHOXY)DODECANOIC ACID. | WASHINGTON UNIVERSITY (US) | 1999-09-28 | — | — | US | disclosed |
| US-5952377-A | SUBSTRATES FOR N-MYRISTOYLTRANSFERASE (NMT) AND/OR ITS ACYL COENZYME, AS ANTI-VIRAL AND ANTI-FUNGAL AGENTS OR PRO-DRUGS; TREATING AIDS, LENTIVIRUSES SUCH AS THE HUMAN IMMUNODEFICIENCY VIRUS | G. D. SEARLE & CO. (US) | 1999-09-14 | — | — | US | disclosed |
| US-5929110-A | USEFUL AS SUBSTRATES FOR N-MYRISTOYLTRANSFERASE (NMT) AND/OR ITS ACYL COENZYME, AND AS ANTI-VIRAL AND ANTI-FUNGAL AGENTS OR PRO-DRUGS OF SUCH AGENTS | G. D. SEARLE & CO. (US) | 1999-07-27 | — | — | US | disclosed |
| US-5871954-A | ACYLATION OF PEPTIDE OR PROTEIN BY REACTING WITH COENZYME A ESTER OF AN OXY- OR THIO-SUBSTITUTED FATTY ACID ANALOG IN PRESENCE OF N-MYRISTOYL TRANSFERASE | WASHINGTON UNIVERSITY (US) | 1999-02-16 | — | — | US | disclosed |
| US-5859052-A | TREATING LENTIVIRUS INFECTIONS, ESPECIALLY HUMAN IMMUNODEFICIENCY VIRUS | G. D. SEARLE & CO. (US) | 1999-01-12 | — | — | US | disclosed |
| US-5744631-A | Fatty acid analogs and prodrugs | G.D. SEARLE & CO. (US) | 1998-04-28 | — | — | US | disclosed |
| US-5670650-A | ANTIVIRAL AND ANTIFUNGAL AGENTS | G. D. SEARLE & CO. (US) | 1997-09-23 | — | — | US | disclosed |
| US-5599947-A | VIRICIDES, FUNGICIDES OR THEIR PRODRUGS | G. D. SEARLE & CO. (US) | 1997-02-04 | — | — | US | disclosed |
| EP-0636134-A1 | NOVEL ACYLATED PHOSPHOLIPID DRUGS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-02-01 | — | — | EP | disclosed |
| WO-1993021191-A1 | NOVEL ACYLATED PHOSPHOLIPID DRUGS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-10-28 | — | — | WO | disclosed |
| EP-0415902-B1 | OXY- OR THIO-SUBSTITUTED FATTY ACID ANALOGS FOR USE IN THE TREATMENT OF RETROVIRAL INFECTIONS | WASHINGTON UNIVERSITY (US) | 1993-03-17 | — | — | EP | disclosed |
| EP-0327523-B1 | NOVEL FATTY ACID ANALOG ENZYME SUBSTRATES | WASHINGTON UNIVERSITY (US) | 1992-06-17 | — | — | EP | disclosed |
| US-5073571-A | Oxy or thio substituted fatty acid or ester | WASHINGTON UNIVERSITY (US) | 1991-12-17 | — | — | US | disclosed |
| EP-0415902-A1 | Oxy- or thio-substituted fatty acid analogs for use in the treatment of retroviral infections | WASHINGTON UNIVERSITY (US) | 1991-03-06 | — | — | EP | disclosed |
| EP-0327523-A1 | Novel fatty acid analog enzyme substrates | WASHINGTON UNIVERSITY (US) | 1989-08-09 | — | — | EP | disclosed |