SCHEMBL7201652

SCHEMBL7201652

Cc1ccc(S(=O)(=O)NCCCCN(CCCN(CCCN(CCCCNS(=O)(=O)c2ccc(C)cc2)S(=O)(=O)c2ccc(C)cc2)Cc2ccccc2)S(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 6/20 0.53
OPRK1 P41145 3/20 0.53
RAB9A P51151 1/20 0.52
CA12 O43570 2/20 0.50
CA9 Q16790 2/20 0.50
TMEM97 Q5BJF2 1/20 0.50
SIGMAR1 Q99720 1/20 0.50
CA2 P00918 1/20 0.50
TAS2R14 Q9NYV8 1/20 0.50
OPRM1 P35372 1/20 0.50
ALDH1A1 P00352 3/20 0.49
LMNA P02545 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
ALOX15 P16050 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
ATM Q13315 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
MEN1 O00255 1/20 0.48
MAPT P10636 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7206800 0.97 CA12 (0.54) CNR2OPRK1RAB9ACA12CA9
SCHEMBL7203881 0.88 CA12 (0.63) OPRK1RAB9ACA12CA9TMEM97
SCHEMBL7207746 0.87 CA12 (0.64) CA12CA9CA2ALDH1A1LMNA
SCHEMBL7095728 0.86 CA12 (0.66) CA12CA9CA2ALDH1A1LMNA
SCHEMBL7204962 0.85 CNR2 (0.59) CNR2TAS2R14HTT
SCHEMBL7097556 0.84 CA12 (0.64) RAB9ACA12CA9CA2ALDH1A1
SCHEMBL7095475 0.84 CA12 (0.68) CA12CA9CA2ALDH1A1LMNA
SCHEMBL7203875 0.84 CA12 (0.64) RAB9ACA12CA9CA2ALDH1A1
SCHEMBL7205364 0.84 CA12 (0.64) RAB9ACA12CA9CA2ALDH1A1
SCHEMBL7092423 0.84 CA12 (0.64) RAB9ACA12CA9CA2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6605645-B2 Such as 1,15-di(cyclopropylmethylamino)-8-benzyl-4,8,12-triazapentadecane; carcinostatic action RIKEN (JP) 2003-08-12 US disclosed
US-20020067472-A1 Linear polyamine compounds and polyamine anticancer agents IWATA MASAAKI (JP) 2002-06-06 US disclosed
US-6319956-B1 N1, N4-BIS(CYCLOPROPYLMETHYLAMINO)TRIALKYLENETETRAMINES THAT MAY BE TOLUENESULFONATED. RIKEN (JP) 2001-11-20 US disclosed