Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7199478 | 0.99 | CNR2 (0.60) | CNR2CNR1TAS2R14POLBMCHR1 | |
| SCHEMBL7206806 | 0.97 | CNR2 (0.61) | CNR2CNR1TAS2R14POLBMCHR1 | |
| SCHEMBL6988598 | 0.88 | CNR2 (0.53) | CNR2CNR1TAS2R14POLB | |
| SCHEMBL7095958 | 0.85 | CNR2 (0.56) | CNR2HTT | |
| SCHEMBL6895598 | 0.85 | CNR2 (0.56) | CNR2HTT | |
| SCHEMBL7206014 | 0.85 | CNR2 (0.56) | CNR2HTT | |
| SCHEMBL7201208 | 0.85 | CNR2 (0.56) | CNR2HTT | |
| SCHEMBL7201652 | 0.85 | CNR2 (0.53) | CNR2TAS2R14HTT | |
| SCHEMBL7204835 | 0.85 | TAS2R14 (0.66) | CNR2CNR1TAS2R14 | |
| SCHEMBL7092691 | 0.84 | CNR2 (0.57) | CNR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605645-B2 | Such as 1,15-di(cyclopropylmethylamino)-8-benzyl-4,8,12-triazapentadecane; carcinostatic action | RIKEN (JP) | 2003-08-12 | — | — | US | disclosed |
| US-20020067472-A1 | Linear polyamine compounds and polyamine anticancer agents | IWATA MASAAKI (JP) | 2002-06-06 | — | — | US | disclosed |
| US-6319956-B1 | N1, N4-BIS(CYCLOPROPYLMETHYLAMINO)TRIALKYLENETETRAMINES THAT MAY BE TOLUENESULFONATED. | RIKEN (JP) | 2001-11-20 | — | — | US | disclosed |