Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.54 |
| ▸ | NOS3 | P29474 | 1/20 | 0.51 |
| ▸ | NOS1 | P29475 | 1/20 | 0.51 |
| ▸ | NOS2 | P35228 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7208611 | 0.86 | SLC6A4 (0.59) | SLC6A4 | |
| SCHEMBL7207614 | 0.86 | SLC6A4 (0.59) | SLC6A4 | |
| SCHEMBL7201252 | 0.85 | SLC6A4 (0.55) | SLC6A4NOS3NOS1NOS2 | |
| SCHEMBL7204002 | 0.85 | SLC6A4 (0.53) | SLC6A4NOS3NOS1 | |
| SCHEMBL7200295 | 0.85 | SLC6A4 (0.59) | SLC6A4 | |
| Oxalic Acid SCHEMBL7208537 | 0.84 | SLC6A4 (0.54) | SLC6A4NOS3NOS1NOS2 | |
| SCHEMBL7205038 | 0.83 | SLC6A4 (0.65) | SLC6A4 | |
| SCHEMBL7204456 | 0.83 | SLC6A4 (0.60) | SLC6A4 | |
| SCHEMBL7206081 | 0.83 | SLC6A4 (0.52) | SLC6A4NOS3NOS1NOS2 | |
| SCHEMBL7207543 | 0.82 | NOS3 (0.56) | SLC6A4NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608079-B1 | Activating serotonin-1F receptors, inhibiting neuronal protein extravasation, treating migraine | ELI LILLY AND COMPANY | 2003-08-19 | — | — | US | disclosed |