SCHEMBL7201769

SCHEMBL7201769

CC(c1ccccc1)c1cccc(C(=O)O)c1C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.44
KMT2A Q03164 2/20 0.44
GAA P10253 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ALOX15 P16050 1/20 0.43
MAPT P10636 2/20 0.41
HDAC8 Q9BY41 1/20 0.41
TYR P14679 1/20 0.41
AKR1C3 P42330 2/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
SRC P12931 1/20 0.39
POLB P06746 1/20 0.39
HCAR2 Q8TDS4 1/20 0.39
NR4A1 P22736 1/20 0.39
NR4A2 P43354 1/20 0.39
NR4A3 Q92570 1/20 0.39
LMNA P02545 2/20 0.39
MYC P01106 1/20 0.39
CDC25B P30305 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29400459 0.89 ALDH1A1 (0.44) ALDH1A1KMT2AGAATDP1ALOX15
SCHEMBL22911 0.89 ALDH1A1 (0.44) ALDH1A1KMT2AGAATDP1ALOX15
SCHEMBL31090829 0.89 ALDH1A1 (0.44) ALDH1A1KMT2AGAATDP1ALOX15
SCHEMBL1854603 0.89 ALDH1A1 (0.41) ALDH1A1KMT2AGAATDP1ALOX15
SCHEMBL19283592 0.89 ALDH1A1 (0.41) ALDH1A1KMT2AGAATDP1ALOX15
SCHEMBL3244675 0.89 ALDH1A1 (0.41) ALDH1A1KMT2AGAATDP1ALOX15
SCHEMBL5549504 0.87 ALDH1A1 (0.43) ALDH1A1KMT2AGAATDP1ALOX15
SCHEMBL584940 0.87 ALDH1A1 (0.55) ALDH1A1KMT2AGAATDP1ALOX15
SCHEMBL10483662 0.86 ANPEP (0.44) ALDH1A1MAPTAKR1C3CYP3A4POLB
SCHEMBL312797 0.83 ALDH1A1 (0.50) ALDH1A1KMT2AGAATDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115297858-A Pharmaceutical composition for treating hypertrophic cardiomyopathy and treatment method using same 赛特瑞恩股份有限公司 2022-11-04 CN disclosed
WO-2003078377-A1 OXIDATION OF O-XYLOL TO FORM O-TOLUIC AND OTHER OXIDATION PRODUCTS BY THE CONTROLLED SUPPLY OF AN OXYGEN-CONTAINING GAS BASF AKTIENGESELLSCHAFT (DE) 2003-09-25 WO disclosed
WO-2003078369-A1 OXIDATION OF O-XYLOL TO FORM O-TOLUIC ACID AND OTHER OXIDATION PRODUCTS BY THE STAGGERED SUPPLY OF AN OXYGEN-CONTAINING GAS BASF AKTIENGESELLSCHAFT (DE) 2003-09-25 WO disclosed