SCHEMBL720178

SCHEMBL720178

C=CCC(CCCC)OC(=O)C(=C)C

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.41
CTSK P43235 3/20 0.35
PLA2G2C Q5R387 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
PRKCA P17252 1/20 0.33
PRKCD Q05655 1/20 0.33
FAAH O00519 1/20 0.33
HPGD P15428 1/20 0.33
LMNA P02545 2/20 0.32
ACHE P22303 1/20 0.32
BACE1 P56817 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
ATM Q13315 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1577727 0.86 TSHR (0.48) TSHRCTSKMAPTMAPK1PRKCA
SCHEMBL3217709 0.85 PRKCA (0.43) TSHRCTSKPLA2G2CMAPTMAPK1
SCHEMBL31757150 0.84 TSHR (0.47) TSHRCTSKMAPTMAPK1PRKCA
SCHEMBL5697412 0.83 TSHR (0.35) TSHRALDH1A1THRB
SCHEMBL1692337 0.83 TSHR (0.46) TSHRCTSKMAPTMAPK1PRKCA
SCHEMBL1493259 0.83 TSHR (0.50) TSHRCTSKMAPTMAPK1PRKCA
SCHEMBL28531896 0.83 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL4132684 0.83 TSHR (0.46) TSHRCTSKMAPK1PRKCAPRKCD
SCHEMBL8058797 0.81 TSHR (0.39) TSHRCTSKMAPTMAPK1PRKCA
SCHEMBL9788309 0.81 TSHR (0.40) TSHRPLA2G2CALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8361631-B2 Polymer blend containing intermediate transfer members XEROX CORPORATION (US) 2013-01-29 US claimed
US-20120049121-A1 POLYMER BLEND CONTAINING INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2012-03-01 US claimed
US-9011988-B2 Liquid-crystal compound, liquid-crystal composition, light absorption anisotropic film, and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-04-21 US disclosed
US-8541935-B2 Color filter and light-emitting display element UDC IRELAND LIMITED (IE) 2013-09-24 US disclosed
US-20130187090-A1 LIQUID-CRYSTAL COMPOUND, LIQUID-CRYSTAL COMPOSITION, LIGHT ABSORPTION ANISOTROPIC FILM, AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-07-25 US disclosed
EP-2554536-A1 LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTALLINE COMPOSITION, ANISOTROPICALLY LIGHT-ABSORBING FILM, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM Corporation (JP) 2013-02-06 EP disclosed
US-8361631-B2 Polymer blend containing intermediate transfer members XEROX CORPORATION (US) 2013-01-29 US disclosed
EP-2478396-A1 COLOR FILTER AND LIGHT-EMITTING DISPLAY ELEMENT FUJIFILM Corporation (JP) 2012-07-25 EP disclosed
US-20120099054-A1 COLOR FILTER AND LIGHT-EMITTING DISPLAY ELEMENT UDC IRELAND LIMITED (IE) 2012-04-26 US disclosed
US-20120049121-A1 POLYMER BLEND CONTAINING INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2012-03-01 US disclosed
WO-2011030883-A1 COLOR FILTER AND LIGHT-EMITTING DISPLAY ELEMENT FUJIFILM CORPORATION (JP) 2011-03-17 WO disclosed