Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 8/20 | 0.38 |
| ▸ | BCL6 | P41182 | 7/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666004 | 0.83 | SRC (0.43) | SRCBCL6DNMT1EHMT2 | |
| Hydrochloric Acid SCHEMBL4664552 | 0.83 | SRC (0.43) | SRCBCL6DNMT1EHMT2 | |
| SCHEMBL4666065 | 0.79 | FGFR1 (0.42) | SRCBCL6 | |
| Hydrochloric Acid SCHEMBL4667705 | 0.78 | FGFR1 (0.42) | SRCBCL6 | |
| SCHEMBL7146159 | 0.77 | MET (0.35) | SRCERBB2 | |
| SCHEMBL4665962 | 0.73 | SRC (0.53) | SRCDNMT1EHMT2 | |
| SCHEMBL4665951 | 0.73 | MAPKAPK2 (0.43) | BCL6 | |
| Hydrochloric Acid SCHEMBL4771269 | 0.73 | SRC (0.52) | SRCDNMT1EHMT2 | |
| SCHEMBL4666088 | 0.71 | PRKCQ (0.52) | SRCDNMT1EHMT2ERBB2 | |
| SCHEMBL4666061 | 0.70 | FGFR2 (0.46) | SRCDNMT1EHMT2ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313726-A1 | QUINOLINE DERIVATIVES HAVING VEGF INHIBITING ACTIVITY | AstraZeneca AB (SE) | 2003-05-28 | — | — | EP | claimed |
| WO-2002012226-A1 | QUINOLINE DERIVATIVES HAVING VEGF INHIBITING ACTIVITY | ASTRAZENECA AB (SE) | 2002-02-14 | — | — | WO | claimed |