Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | BAX | Q07812 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12227827 | 0.87 | KMT2A (0.41) | SMN1; SMN2MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL6931945 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2RAD52BAXMAPTCYP3A4 | |
| SCHEMBL11438133 | 0.77 | SMN1; SMN2 (0.60) | SMN1; SMN2RAD52BAXMAPTCYP3A4 | |
| Sulfuric Acid SCHEMBL28700688 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2RAD52BAXMAPTCYP3A4 | |
| SCHEMBL1408785 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2RAD52BAXMAPTCYP3A4 | |
| SCHEMBL25262548 | 0.75 | SMN1; SMN2 (0.44) | SMN1; SMN2RAD52BAXMAPTCYP3A4 | |
| SCHEMBL151400 | 0.75 | SMN1; SMN2 (0.58) | SMN1; SMN2RAD52BAXMAPTCYP3A4 | |
| SCHEMBL2801591 | 0.74 | SMN1; SMN2 (0.54) | SMN1; SMN2RAD52BAXMAPTCYP3A4 | |
| SCHEMBL25948687 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2RAD52BAXMAPTCYP3A4 | |
| SCHEMBL7286319 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2RAD52BAXMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030110840-A1 | Systems and methods for detecting a particle | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2003-06-19 | — | — | US | disclosed |
| US-6482799-B1 | Self-preserving multipurpose ophthalmic solutions incorporating a polypeptide antimicrobial | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-11-19 | — | — | US | disclosed |
| WO-2000071175-A1 | OPHTHALMIC SOLUTIONS INCORPORATING AN ANTIMICROBIAL POLYPEPTIDE | LARGE SCALE BIOLOGY CORPORATION (US) | 2000-11-30 | — | — | WO | disclosed |
| EP-0524604-B1 | Process for the preparations of S-(+)-2,2-dimethyl-cyclopropane carboxamid by genetically engineered microorganismes | LONZA AG (CH) | 1998-10-14 | — | — | EP | disclosed |
| EP-0502525-B1 | Biotechnological process for the production of S-(+)-2,2-dimethylcyclopropanecarboxamide and R-(-)-2,2-dimethylcyclopropanecarboxylic acid | LONZA AG (CH) | 1996-06-26 | — | — | EP | disclosed |
| US-5427934-A | A new DNA isolation from microorganism that codes for a stereospecific hydrolase, ligation of DNA in expression vector results hybrid plasmid, which is transformed in microorganism, which biotransform amide to acid and isomer of amide | LONZA LTD. (CH) | 1995-06-27 | — | — | US | disclosed |
| US-5360731-A | Bacteria capable of stereospecifically hydrolyzing R-(-)-2,2-dimethylcyclopropanecarboxamide | LONZA LTD. (CH) | 1994-11-01 | — | — | US | disclosed |
| US-5273903-A | Biotransforming the R(-) isomer in a racemic mixture with Comamonas or an enzyme from this microorganism | LONZA LTD. (CH) | 1993-12-28 | — | — | US | disclosed |
| EP-0524604-A2 | Process for the preparations of S-(+)-2,2-dimethyl-cyclopropane carboxamid by genetically engineered microorganismes | LONZA A.G. (CH) | 1993-01-27 | — | — | EP | disclosed |
| EP-0502525-A1 | Biotechnological process for the production of S-(+)-2,2-dimethylcyclopropanecarboxamide and R-(-)-2,2-dimethylcyclopropanecarboxylic acid | LONZA AG (CH) | 1992-09-09 | — | — | EP | disclosed |