SCHEMBL2801591

SCHEMBL2801591

CCCC(O)CN1CCNCC1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.54
RAD52 P43351 1/20 0.44
IDO1 P14902 1/20 0.42
BAX Q07812 1/20 0.41
MAPT P10636 2/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
ALOX15 P16050 1/20 0.40
MAPK1 P28482 1/20 0.40
POLB P06746 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
SIGMAR1 Q99720 2/20 0.39
ATM Q13315 1/20 0.38
USP2 O75604 1/20 0.38
CHRM5 P08912 1/20 0.37
CHRM3 P20309 1/20 0.37
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14096698 0.89 SMN1; SMN2 (0.51) SMN1; SMN2RAD52IDO1BAXMAPT
SCHEMBL11039479 0.87 SMN1; SMN2 (0.50) SMN1; SMN2RAD52IDO1BAXMAPT
SCHEMBL10890793 0.85 SMN1; SMN2 (0.49) SMN1; SMN2RAD52IDO1SIGMAR1ALDH1A1
SCHEMBL31467395 0.85 SMN1; SMN2 (0.49) SMN1; SMN2RAD52IDO1SIGMAR1ALDH1A1
SCHEMBL11668191 0.85
SCHEMBL2800684 0.85 KMT2A (0.48) SMN1; SMN2MAPTALOX15MEN1KMT2A
SCHEMBL6380664 0.84 SMN1; SMN2 (0.47) SMN1; SMN2RAD52IDO1SIGMAR1ALDH1A1
SCHEMBL24319375 0.83 SMN1; SMN2 (0.58) SMN1; SMN2RAD52IDO1BAXMAPT
SCHEMBL2800007 0.83 SMN1; SMN2 (0.58) SMN1; SMN2RAD52IDO1BAXMAPT
SCHEMBL17934826 0.83 SMN1; SMN2 (0.58) SMN1; SMN2RAD52IDO1BAXMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US claimed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP claimed
US-9994515-B2 Aryl naphthyl methanone oxime(s) and process for preparation thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2018-06-12 US disclosed
EP-3039010-B1 ARYL NAPHTHYL METHANONE OXIME(S) AND PROCESS FOR PREPARATION THEREOF COUNCIL SCIENT IND RES (IN) 2017-10-11 EP disclosed
US-20160304442-A1 ARYL NAPHTHYL METHANONE OXIME(S) AND PROCESS FOR PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-10-20 US disclosed
US-20140350081-A1 INSECT G-COUPLED RECEPTORS USEFUL AS TARGETS FOR INSECTICIDES AND COMPOUNDS AND REAGENTS IDENTIFIED USING THE SAME US ARMY, SECRETARY OF THE ARMY 2014-11-27 US disclosed
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US disclosed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP disclosed
US-20130190474-A1 EPICHLOROHYDRIN, MANUFACTURING PROCESS AND USE SOLVAY SA (BE) 2013-07-25 US disclosed
US-20130137646-A1 METHODS OF TREATMENT, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-05-30 US disclosed
US-20130102755-A1 PRODUCT CONTAINING EPICHLOROHYDRIN, ITS PREPARATION AND ITS USE IN VARIOUS APPLICATIONS SOLVAY SA (BE) 2013-04-25 US disclosed
US-20030078185-A1 Polyelectrolyte complexes and a method for production thereof BASF AKTIENGESELLSCHAFT (DE) 2003-04-24 US disclosed
WO-2003031559-A1 METHOD FOR MANUFACTURING LAUNDRY ADDITIVE ARTICLE THE PROCTER & GAMBLE COMPANY (US) 2003-04-17 WO disclosed
EP-1280880-A2 LAUNDRY DETERGENT COMPOSITIONS CONTAINING A POLYMER THE PROCTER & GAMBLE COMPANY (US) 2003-02-05 EP disclosed
WO-2002033040-A1 LAUNDERING AID FOR PREVENTING DYE TRANSFER THE PROCTER & GAMBLE COMPANY (US) 2002-04-25 WO disclosed
US-20010056058-A1 Laundry detergent compositions containing a polymer for fabric appearance improvement THE PROCTER & GAMBLE COMPANY 2001-12-27 US disclosed
WO-2001085891-A2 LAUNDRY DETERGENT COMPOSITIONS CONTAINING A POLYMER THE PROCTER & GAMBLE COMPANY (US) 2001-11-15 WO disclosed
US-6147183-A Amphoteric amine based polymers having a net cationic charge and process for their production BASF AKTIENGESELLSCHAFT (DE) 2000-11-14 US disclosed
US-6111056-A Cyclic amine based polymers and process for their production BASF AKTIENGESELLSCHAFT (DE) 2000-08-29 US disclosed
US-4946612-A Lubricating oil composition for sliding surface and for metallic working and method for lubrication of machine tools using said composition IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140350081-A1 INSECT G-COUPLED RECEPTORS USEFUL AS TARGETS FOR INSECTICIDES AND COMPOUNDS AND REAGENTS IDENTIFIED USING THE SAME DDT, ADRA2C, MCHR1 SMN1; SMN2 3615/4885RAD52 1738/4885IDO1 1236/4885
US-20160304442-A1 ARYL NAPHTHYL METHANONE OXIME(S) AND PROCESS FOR PREPARATION THEREOF MCL1, CYP11B1, CYP21A2 SMN1; SMN2 626/4885RAD52 1580/4885IDO1 2060/4885
US-20130137646-A1 METHODS OF TREATMENT, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF SLC5A2, SLC5A1, SLC2A2 SMN1; SMN2 1248/4885RAD52 4743/4885IDO1 1416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.