SCHEMBL7201890

SCHEMBL7201890

CCOCCc1cccc(C(=O)O)c1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.47
PPARA Q07869 3/20 0.43
BID P55957 3/20 0.43
MCL1 Q07820 3/20 0.43
KAT8 Q9H7Z6 3/20 0.43
BCL2L1 Q07817 2/20 0.43
BAK1 Q16611 2/20 0.43
PPARG P37231 2/20 0.43
EP300 Q09472 2/20 0.43
KAT5 Q92993 2/20 0.43
KAT2A Q92830 1/20 0.43
KAT2B Q92831 1/20 0.43
SAE1 Q9UBE0 1/20 0.43
KDM4E B2RXH2 1/20 0.42
POLB P06746 1/20 0.42
CLCN2 P51788 1/20 0.41
HMGB1 P09429 1/20 0.41
ALDH1A1 P00352 1/20 0.38
KMT2A Q03164 1/20 0.38
PTK2B Q14289 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10630638 0.87 PPARA (0.44) FOLH1PPARABIDMCL1KAT8
SCHEMBL3681327 0.87 BID (0.50) FOLH1PPARABIDMCL1KAT8
SCHEMBL12197595 0.85 KDM4E (0.49) FOLH1PPARABIDMCL1KAT8
SCHEMBL3966145 0.85 FOLH1 (0.56) FOLH1KDM4EPOLBCLCN2ALDH1A1
SCHEMBL31245538 0.85 FOLH1 (0.56) FOLH1KDM4EPOLBCLCN2ALDH1A1
SCHEMBL9387945 0.84 BID (0.55) PPARABIDMCL1KAT8BCL2L1
SCHEMBL14831561 0.84 KDM4E (0.48) FOLH1PPARABIDMCL1KAT8
SCHEMBL14831563 0.84 KDM4E (0.48) FOLH1PPARABIDMCL1KAT8
SCHEMBL9011107 0.84 FOLH1 (0.49) FOLH1PPARABIDMCL1KAT8
SCHEMBL21753093 0.83 FOLH1 (0.51) FOLH1BIDMCL1BCL2L1BAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9365951-B2 Negative polarity on the nanofiber line KIMBERLY-CLARK WORLDWIDE, INC. (US) 2016-06-14 US disclosed
US-20150211149-A1 Negative Polarity on the Nanofiber Line KIMBERLY-CLARK WORLDWIDE, INC. (US) 2015-07-30 US disclosed
US-20150090658-A1 Fiber having a Nanohair Surface Topography KIMBERLY-CLARK WORLDWIDE, INC. (US) 2015-04-02 US disclosed
US-20030215506-A1 Methods and compositions for enhancement of creatine transport KUHRTS ERIC H (US) 2003-11-20 US disclosed
EP-0340618-B1 Organic composition containing a fluoroalkyl sulfonic acid salt DOW CHEMICAL CO (US) 1996-02-28 EP disclosed
EP-0586575-A1 DEGRADABLE CELLULOSE POLYMERS BATTELLE MEMORIAL INSTITUTE (US) 1994-03-16 EP disclosed
WO-1992020738-A1 DEGRADABLE CELLULOSE POLYMERS BATTELLE MEMORIAL INSTITUTE (US) 1992-11-26 WO disclosed
US-5068233-A For treatment of asthma, antiallergens or antihistamines ASTA PHARMA AKTIENGESELLSCHAFT (DE) 1991-11-26 US disclosed
EP-0340618-A1 Organic composition containing a fluoroalkyl sulfonic acid salt THE DOW CHEMICAL COMPANY (US) 1989-11-08 EP disclosed
US-4806571-A ANTISTATIC AGENTS THE DOW CHEMICAL COMPANY (US) 1989-02-21 US disclosed
US-4618630-A ESPECIALLY FOR POLYURETHANE FOAM PRODUCTION THE DOW CHEMICAL CO. (US) 1986-10-21 US disclosed
WO-1986001521-A1 AN ADDITIVE COMPOSITION FOR INCREASING THE CONDUCTIVITY OF AN ORGANIC POLYMER, AN ACTIVE HYDROGEN-CONTAINING COMPOSITION CONTAINING THE ADDITIVE COMPOSITION, AND AN ORGANIC POLYMER COMPOSITION CONTAINING THE ADDITIVE COMPOSITION THE DOW CHEMICAL COMPANY (US) 1986-03-13 WO disclosed