SCHEMBL9011107

SCHEMBL9011107

COCCc1cccc(C(=O)O)c1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.49
TSHR P16473 1/20 0.46
PPARA Q07869 3/20 0.46
MAPK1 P28482 1/20 0.44
HMGB1 P09429 1/20 0.42
BID P55957 3/20 0.42
MCL1 Q07820 3/20 0.42
BCL2L1 Q07817 2/20 0.42
BAK1 Q16611 2/20 0.42
KAT8 Q9H7Z6 2/20 0.42
PPARG P37231 2/20 0.42
EP300 Q09472 1/20 0.42
KAT2A Q92830 1/20 0.42
KAT2B Q92831 1/20 0.42
KAT5 Q92993 1/20 0.42
SAE1 Q9UBE0 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9011058 0.89 PPARA (0.52) FOLH1PPARABIDMCL1BCL2L1
SCHEMBL8245934 0.84 FOLH1 (0.59) FOLH1TSHRMAPK1HTT
SCHEMBL7201890 0.84 FOLH1 (0.47) FOLH1PPARAHMGB1BIDMCL1
SCHEMBL22912 0.84 FOLH1 (0.59) FOLH1TSHRPPARAHMGB1BID
SCHEMBL27697961 0.82 ALDH1A1 (0.45) PPARABIDMCL1BCL2L1BAK1
SCHEMBL1355661 0.81 BID (0.53) FOLH1PPARAHMGB1BIDMCL1
SCHEMBL31319546 0.81 BID (0.53) FOLH1PPARAHMGB1BIDMCL1
Hydrochloric Acid SCHEMBL28495555 0.81 G6PD (0.50) FOLH1TSHRMAPK1HMGB1HTT
SCHEMBL3680999 0.81 ALDH1A1 (0.55) FOLH1TSHR
SCHEMBL10885451 0.80 BID (0.56) FOLH1PPARAHMGB1BIDMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0494169-B1 Process for the preparation of charged thermosetting polyurethane compositions and homogeneous and stable suspensions of the charge JAYMO S N C (FR) 1996-11-13 EP claimed
US-5238969-A PROCESS FOR THE PREPARATION OF CHARGED THERMOSETTING COMPOUNDS OF THE POLYURETHANE TYPE AND COMPOUNDS OBTAINED THEREBY OMYA S.A. (FR) 1993-08-24 US claimed
US-11123950-B2 Artificial leather sheet and method for manufacturing thereof Kolon Giotech, Inc. (KR) 2021-09-21 US disclosed
US-20190255806-A1 ARTIFICIAL LEATHER SHEET AND METHOD FOR MANUFACTURING THEREOF KOLON INDUSTRIES, INC. (KR) 2019-08-22 US disclosed
CN-104619690-B Method for producing glycolide having rectification step by gas-liquid countercurrent contact, and method for refining crude glycolide 株式会社吴羽 2016-10-12 CN disclosed