Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7201576 | 0.83 | MAPKAPK2 (0.38) | MAPTCYP3A4ALOX15CNR1CASP1 | |
| SCHEMBL13272516 | 0.78 | MAPKAPK2 (0.49) | MAPTCYP3A4ALOX15CNR1CASP1 | |
| SCHEMBL13251070 | 0.78 | MAPKAPK2 (0.49) | MAPTCYP3A4ALOX15CNR1CASP1 | |
| SCHEMBL31499214 | 0.75 | NQO1 (0.62) | CYP1A1CYP1B1KDM4ENPSR1RXFP1 | |
| SCHEMBL906936 | 0.75 | NQO1 (0.62) | CYP1A1CYP1B1KDM4ENPSR1RXFP1 | |
| SCHEMBL7204491 | 0.74 | MEN1 (0.50) | MAPTCYP3A4SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7229011 | 0.73 | HRH2 (0.47) | MAPTCYP1A1CYP1B1MAPKAPK2KDM4E | |
| SCHEMBL28363455 | 0.72 | CYP1A1 (0.53) | MAPTCYP3A4ALOX15CNR1CASP1 | |
| SCHEMBL13098025 | 0.72 | CYP11B1 (0.51) | KDM4ESNCAHPGDSNQO1MEN1 | |
| SCHEMBL6100448 | 0.72 | NQO1 (0.59) | CYP1A1CYP1B1KDM4ENPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6599921-B2 | Antiproliferative agents against estrogen-dependent cancer cells dibenzothiopyran, dibenzopyran and phenanthrene derivatives | NANODESIGN, INC. (CA) | 2003-07-29 | — | — | US | disclosed |
| US-20020156077-A1 | Non-steroidal estrogen receptor ligands | PALOMA PHARMACEUTICALS, INC. | 2002-10-24 | — | — | US | disclosed |
| WO-2002066428-A2 | NON-STEROIDAL ESTROGEN RECEPTOR LIGANDS | NANODESIGN INC. (CA) | 2002-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156077-A1 | Non-steroidal estrogen receptor ligands | ESRRA, ESRRB, ESRRG | MAPT 4642/4885CYP3A4 836/4885ALOX15 1163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.