Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7201989 | 0.83 | MAPT (0.43) | MAPKAPK2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL7205812 | 0.77 | ESR2 (0.55) | MAPTKDM4EALDH1A1HPGDCYP3A4 | |
| SCHEMBL13251070 | 0.76 | MAPKAPK2 (0.49) | MAPKAPK2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL13272516 | 0.76 | MAPKAPK2 (0.49) | MAPKAPK2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL7205506 | 0.74 | ESR1 (0.57) | KDM4EALDH1A1HPGDRXFP1SMN1; SMN2 | |
| SCHEMBL7229011 | 0.74 | HRH2 (0.47) | MAPKAPK2MAPK14MAPTKDM4EALDH1A1 | |
| SCHEMBL15823025 | 0.71 | CYP1A1 (0.51) | MAPKAPK2MAPTCYP3A4ALOX15CNR1 | |
| SCHEMBL30966882 | 0.69 | RAB9A (0.41) | MAPKAPK2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL13408700 | 0.69 | ACACA (0.59) | MAPTKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL13098025 | 0.68 | CYP11B1 (0.51) | KDM4ECYP11B1CYP11B2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6599921-B2 | Antiproliferative agents against estrogen-dependent cancer cells dibenzothiopyran, dibenzopyran and phenanthrene derivatives | NANODESIGN, INC. (CA) | 2003-07-29 | — | — | US | disclosed |
| US-20020156077-A1 | Non-steroidal estrogen receptor ligands | PALOMA PHARMACEUTICALS, INC. | 2002-10-24 | — | — | US | disclosed |
| WO-2002066428-A2 | NON-STEROIDAL ESTROGEN RECEPTOR LIGANDS | NANODESIGN INC. (CA) | 2002-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156077-A1 | Non-steroidal estrogen receptor ligands | ESRRA, ESRRB, ESRRG | MAPKAPK2 3933/4885MAPK14 2204/4885MAPT 4642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.