Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BCL9 | O00512 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202037 | 1.00 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL25823 | 0.88 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL25822 | 0.88 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL7680649 | 0.87 | RECQL (0.43) | CYSLTR2CYSLTR1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL27164 | 0.86 | LMNA (0.38) | CYSLTR2CYSLTR1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL26588 | 0.83 | MAPT (0.43) | MAPTKMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL26589 | 0.83 | MAPT (0.43) | MAPTKMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7200631 | 0.81 | KMT2A (0.41) | MAPTKMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7200623 | 0.81 | KMT2A (0.41) | MAPTKMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL25821 | 0.80 | TDP1 (0.42) | CYSLTR2CYSLTR1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030158089-A1 | Administrative agents via the SMVT transporter | XENOPORT, INC. | 2003-08-21 | — | — | US | disclosed |