SCHEMBL7202183

SCHEMBL7202183

COC(=O)/C(C(=O)O)=C(/C(=O)O)C(=O)OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
EGLN1 Q9GZT9 1/20 0.40
TET2 Q6N021 1/20 0.35
TGFBR1 P36897 1/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
GAA P10253 2/20 0.34
KDM4E B2RXH2 2/20 0.34
MAPT P10636 2/20 0.34
HCAR2 Q8TDS4 2/20 0.33
TSHR P16473 2/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
POLB P06746 4/20 0.32
TDP1 Q9NUW8 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
PKM P14618 1/20 0.32
CYP2C9 P11712 1/20 0.31
DNMT1 P26358 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4824225 0.85 ALDH1A1 (0.43) ALDH1A1EGLN1TET2TGFBR1MEN1
SCHEMBL455415 0.83 ALDH1A1 (0.42) ALDH1A1EGLN1TET2TGFBR1MEN1
SCHEMBL10797814 0.82 ALDH1A1 (0.50) ALDH1A1EGLN1TET2MEN1KMT2A
SCHEMBL31298787 0.79 ALDH1A1 (0.33) ALDH1A1EGLN1
SCHEMBL27895680 0.79 EGLN1 (0.37) ALDH1A1EGLN1TET2TGFBR1TSHR
SCHEMBL126786 0.79
Oxalic Acid SCHEMBL21633322 0.79 ALDH1A1 (0.47) ALDH1A1EGLN1TET2TGFBR1GAA
SCHEMBL22129974 0.76
Rubidium SCHEMBL7042595 0.76
Methyl Alcohol SCHEMBL29001109 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6602589-B2 Formed by extrusion of an olefin-based thermoplastic elastomer or vulcanizate; contains a novel compatibilizer which allows thermoplastic polyurethane to bond to graft polymer of polypropylene ADVANCED ELASTOMER SYSTEMS, L.P. 2003-08-05 US disclosed
US-20020091182-A1 Olefinic slip-coating for automotive weatherseals EXXONMOBIL CHEMICAL PATENTS INC. 2002-07-11 US disclosed
US-6368700-B1 BLEND OF UNSATURATED POLYER, THERMOPLASTIC POLYURETHANE AND ALPHA-OLEFIN ADVANCED ELASTOMER SYSTEMS, L.P. 2002-04-09 US disclosed
EP-0489495-B1 Modified halogenated polyolefin adhesives LORD CORP (US) 1996-03-06 EP disclosed
EP-0633301-A2 Modified halogenated polyolefin adhesives LORD CORPORATION (US) 1995-01-11 EP disclosed
EP-0489495-A2 Modified halogenated polyolefin adhesives LORD CORPORATION (US) 1992-06-10 EP disclosed
US-5102956-A Graft with acid anhydride, modified by polyhydroxylic aromatic compound and sulfur containing compounds to improved peel strength LORD CORPORATION (US) 1992-04-07 US disclosed
US-4822688-A PROPYLENE-ANHYDRIDE GRAFT POLYMER REACTED WITH DIAMINE NOGUES PIERRE (FR) 1989-04-18 US disclosed
US-4735992-A COATINGS FOR METALS SOCIETE ATOCHEM (FR) 1988-04-05 US disclosed
US-4727120-A MALEIC ANHYDRIDE AND DIOL GRAFT POLYMERS SOCIETE ATOCHEM (FR) 1988-02-23 US disclosed