Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CA3 | P07451 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3903921 | 0.90 | KDM4E (0.55) | MAPTKDM4EALDH1A1HPGDMAOB | |
| SCHEMBL30842189 | 0.90 | KDM4E (0.55) | MAPTKDM4EALDH1A1HPGDMAOB | |
| SCHEMBL29191709 | 0.86 | MEN1 (0.62) | MAPTKDM4EALDH1A1HPGDMAOB | |
| SCHEMBL6990963 | 0.84 | ALDH1A1 (0.55) | MAPTKDM4EALDH1A1HPGDMAOB | |
| SCHEMBL3084121 | 0.83 | CYP3A4 (0.50) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL4199370 | 0.82 | MAPT (0.55) | MAPTKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL8136068 | 0.82 | KDM4E (0.59) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL3999898 | 0.80 | KDM4E (0.55) | MAPTKDM4EALDH1A1CA12CA2 | |
| SCHEMBL4254412 | 0.80 | ALDH1A1 (0.54) | MAPTKDM4EALDH1A1HPGDMAOB | |
| SCHEMBL4254408 | 0.80 | ALDH1A1 (0.54) | MAPTKDM4EALDH1A1HPGDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602903-B2 | Substituted O- and/or S heterocyclic compounds; powerful ligands for melatoninergic receptors. | LES LABORATORIES SERVIER (FR) | 2003-08-05 | — | — | US | disclosed |
| US-6313160-B1 | FOR THERAPY AND PROPHYLAXIS OF MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-11-06 | — | — | US | disclosed |