Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 16/20 | 1.00 |
| ▸ | CPB1 | P15086 | 6/20 | 0.82 |
| ▸ | TRHR | P34981 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | GGT1 | P19440 | 1/20 | 0.38 |
| ▸ | TRHDE | Q9UKU6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3839300 | 1.00 | CPB2 (1.00) | CPB2CPB1TRHRSMYD3GGT1 | |
| SCHEMBL6268747 | 0.90 | CPB2 (1.00) | CPB2CPB1GGT1TRHDE | |
| SCHEMBL3839535 | 0.90 | CPB2 (1.00) | CPB2CPB1GGT1TRHDE | |
| SCHEMBL3845162 | 0.88 | CPB2 (0.93) | CPB2CPB1 | |
| SCHEMBL3838506 | 0.88 | CPB2 (1.00) | CPB2CPB1GGT1TRHDE | |
| SCHEMBL3841445 | 0.87 | CPB2 (0.77) | CPB2CPB1GGT1TRHDE | |
| SCHEMBL3844062 | 0.85 | CPB2 (0.79) | CPB2CPB1GGT1 | |
| SCHEMBL3843789 | 0.84 | CPB2 (0.73) | CPB2CPB1TRHRGGT1 | |
| SCHEMBL3842771 | 0.83 | CPB2 (0.71) | CPB2CPB1TRHRTRHDE | |
| SCHEMBL25474836 | 0.82 | CPB2 (0.70) | CPB2CPB1TRHRSMYD3TRHDE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311488-A1 | SUBSTITUTED IMIDAZOLES AS TAFIA INHIBITORS | Pfizer Limited (GB) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014285-A1 | SUBSTITUTED IMIDAZOLES AS TAFIA INHIBITORS | PFIZER LIMITED (GB) | 2002-02-21 | — | — | WO | disclosed |