Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 12/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 10/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 8/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5036503 | 0.89 | SMN1; SMN2 (0.42) | ENPP3ENPP1ENPP2SMN1; SMN2POLB | |
| SCHEMBL5037872 | 0.89 | SMN1; SMN2 (0.42) | ENPP3ENPP1ENPP2SMN1; SMN2POLB | |
| SCHEMBL5040663 | 0.89 | SMN1; SMN2 (0.42) | ENPP3ENPP1ENPP2SMN1; SMN2POLB | |
| SCHEMBL5036884 | 0.84 | SMN1; SMN2 (0.43) | ENPP3ENPP1ENPP2SMN1; SMN2POLB | |
| SCHEMBL5042929 | 0.81 | SMN1; SMN2 (0.44) | ENPP3ENPP1ENPP2SMN1; SMN2POLB | |
| SCHEMBL5037583 | 0.81 | ENPP3 (0.43) | ENPP3ENPP1ENPP2SMN1; SMN2POLB | |
| SCHEMBL5037874 | 0.81 | SMN1; SMN2 (0.44) | ENPP3ENPP1ENPP2SMN1; SMN2POLB | |
| SCHEMBL5037835 | 0.80 | ENPP3 (0.44) | ENPP3ENPP1ENPP2SMN1; SMN2 | |
| SCHEMBL5040947 | 0.80 | ENPP3 (0.44) | ENPP3ENPP1ENPP2SMN1; SMN2 | |
| SCHEMBL5036401 | 0.80 | ENPP3 (0.42) | ENPP3ENPP1ENPP2SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432417-A2 | SUBSTITUTED BENZIMIDAZOLE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCER | Aventis Pharma S.A. (FR) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003028721-A2 | SUBSTITUTED BENZIMIDAZOLE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCER | AVENTIS PHARMA S.A. (FR) | 2003-04-10 | — | — | WO | disclosed |