SCHEMBL7202465

SCHEMBL7202465

C#CC(O)c1ccc(OCCC)cc1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.47
ACACB O00763 10/20 0.47
ACACA Q13085 5/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
GPR88 Q9GZN0 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
PLK1 P53350 1/20 0.42
LMNA P02545 1/20 0.41
CXCL12 P48061 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15010950 0.93 LTA4H (0.47) LTA4H
SCHEMBL7204275 0.86 NQO1 (0.52) LTA4HACACBMEN1KMT2AL3MBTL1
SCHEMBL28687086 0.85 ACACB (0.40) ACACBGPR88
SCHEMBL10681683 0.83 LTA4H (0.47) LTA4HACACBACACAMEN1KMT2A
SCHEMBL15906508 0.82 LTA4H (0.46) LTA4HACACBACACAMEN1KMT2A
SCHEMBL6966050 0.81 KDM4E (0.54)
SCHEMBL7201248 0.79 FFAR1 (0.36) ACACBL3MBTL1LMNA
SCHEMBL7202031 0.79 CA12 (0.46)
SCHEMBL28886897 0.78 LTA4H (0.53) LTA4HACACBACACAMEN1KMT2A
SCHEMBL11786262 0.77 LTA4H (0.52) LTA4HACACBACACAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6605730-B2 3-(2-Thienyl)-5-phenyl-1H-pyrazole compounds of given formula NIHON BAYER AGROCHEM K.K. (JP) 2003-08-12 US disclosed
US-20030028034-A1 Nematicidal pyrazoles WADA KATSUAKI (JP) 2003-02-06 US disclosed
US-6310049-B1 3-(2-THIENYL),5-(SUBSTITUTED PHENYL)-1H-PYRAZOLES AND 3-(SUBSTITUTED PHENYL),5-(2-THIENYL)-1H-PYRAZOLES OF GIVEN FORMULA; ANTHELMINTICS NIHON BAYER AGROCHEM K.K. (JP) 2001-10-30 US disclosed
EP-1104418-A2 NEMATICIDAL PYRAZOLES NIHON BAYER AGROCHEM K.K. (JP) 2001-06-06 EP disclosed
WO-2000009500-A2 NEMATICIDAL PYRAZOLES NIHON BAYER AGROCHEM K.K. (JP) 2000-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030028034-A1 Nematicidal pyrazoles CBR3, CBR1, CCR4 LTA4H 751/4885ACACB 827/4885ACACA 897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.