Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 14/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | LTK | P29376 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463365 | 0.80 | AHR (0.64) | AHRCDK1CCNB1MAOB | |
| SCHEMBL6463848 | 0.78 | AHR (0.60) | AHRALOX5CDK1CCNB1 | |
| SCHEMBL9215395 | 0.77 | AHR (0.73) | AHR | |
| SCHEMBL8134191 | 0.75 | AHR (0.57) | AHRCDK1CCNB1MEN1KMT2A | |
| SCHEMBL1804174 | 0.74 | AHR (1.00) | AHR | |
| SCHEMBL2281295 | 0.69 | AHR (1.00) | AHR | |
| SCHEMBL6472813 | 0.68 | AHR (0.64) | AHRMAOB | |
| SCHEMBL8120005 | 0.68 | AHR (0.64) | AHR | |
| SCHEMBL1803931 | 0.67 | AHR (0.68) | AHRMEN1KMT2A | |
| SCHEMBL29375526 | 0.67 | AHR (0.68) | AHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140047-B1 | ENDOCRINE THERAPY FOR BREAST CANCER: COMBINED TREATMENT WITH TAMOXIFEN PLUS ALKYL PCDFS | TEXAS A & M UNIV SYS (US) | 2003-10-29 | — | — | EP | disclosed |
| EP-1140047-A2 | ENDOCRINE THERAPY FOR BREAST CANCER: COMBINED TREATMENT WITH TAMOXIFEN PLUS ALKYL PCDFS | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2001-10-10 | — | — | EP | disclosed |
| US-6136845-A | ANTITUMOR AGENTS; MIXTURE CONTAINING POLYCHLORINATED DIBENZOFURAN | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2000-10-24 | — | — | US | disclosed |
| WO-2000037065-A2 | ENDOCRINE THERAPY FOR BREAST CANCER: COMBINED TREATMENT WITH TAMOXIFEN PLUS ALKYL PCDFS | THE TEXAS A & M UNIVERSITY SYSTEM (US) | 2000-06-29 | — | — | WO | disclosed |