Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 11/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463848 | 0.91 | AHR (0.60) | AHRMAPTSIRT2ALDH1A1KDM4E | |
| SCHEMBL6463365 | 0.85 | AHR (0.64) | AHRALDH1A1CDK1CCNB1 | |
| SCHEMBL9215395 | 0.79 | AHR (0.73) | AHR | |
| SCHEMBL7202544 | 0.75 | AHR (0.59) | AHRMEN1KMT2ACDK1CCNB1 | |
| SCHEMBL1804174 | 0.73 | AHR (1.00) | AHR | |
| SCHEMBL1803931 | 0.72 | AHR (0.68) | AHRMEN1KMT2A | |
| SCHEMBL29375526 | 0.72 | AHR (0.68) | AHRMEN1KMT2A | |
| SCHEMBL8120005 | 0.70 | AHR (0.64) | AHR | |
| SCHEMBL6472813 | 0.70 | AHR (0.64) | AHR | |
| SCHEMBL2281295 | 0.68 | AHR (1.00) | AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140063-A | USE OF THE ARYL HYDROCARBON (AH) RECEPTOR PROTEIN COMPLEX AS A DRUG TARGET, ALONE OR IN COMBINATION WITH ANOTHER COMPOUND, TO TREAT CYTOPATHIC CELL CHANGES AND VIRAL INFECTIONS GENERALLY | PARACELSIAN, INC. (US) | 2000-10-31 | — | — | US | disclosed |