SCHEMBL7202717

SCHEMBL7202717

O=C(O)c1cc(C(=O)O)c(C(=O)O)c(-c2ccccc2C(=O)O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25A P30304 1/20 0.49
CDC25B P30305 1/20 0.49
HSD17B10 Q99714 1/20 0.49
FOLH1 Q04609 2/20 0.47
CYP2C9 P11712 2/20 0.46
CYP3A4 P08684 1/20 0.46
ALOX12 P18054 1/20 0.46
AKR1C3 P42330 1/20 0.46
ALDH1A1 P00352 3/20 0.45
ALOX15 P16050 1/20 0.45
TTR P02766 2/20 0.44
KDM4E B2RXH2 2/20 0.44
USP2 O75604 1/20 0.44
TSHR P16473 1/20 0.44
GAA P10253 1/20 0.44
PTPRC P08575 2/20 0.43
MYC P01106 1/20 0.43
CYP2C8 P10632 1/20 0.43
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30223654 0.86 HNF4A (0.46) CDC25ACDC25BHSD17B10FOLH1AKR1C3
SCHEMBL9423207 0.84 PTPN1 (0.47) CDC25ACDC25BHSD17B10FOLH1AKR1C3
SCHEMBL30883369 0.82 PTPN1 (0.46) CDC25ACDC25BHSD17B10FOLH1AKR1C3
SCHEMBL809021 0.81 FOLH1 (0.61) HSD17B10FOLH1CYP2C9CYP3A4ALOX12
SCHEMBL9778069 0.80 TTR (0.38) CDC25ACDC25BHSD17B10AKR1C3ALDH1A1
SCHEMBL10787725 0.79 TTR (0.58) CDC25ACDC25BHSD17B10FOLH1CYP2C9
SCHEMBL27893408 0.79 DDT (0.57) CDC25ACDC25BHSD17B10FOLH1AKR1C3
SCHEMBL2791940 0.79 HSD17B10 (0.44) CDC25ACDC25BHSD17B10FOLH1KDM4E
SCHEMBL29369532 0.79 FOLH1 (0.59) CDC25ACDC25BHSD17B10FOLH1CYP2C9
SCHEMBL10783624 0.79 PTPN1 (0.50) CDC25ACDC25BHSD17B10FOLH1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6596838-B1 Electrodialysis, electroosmosis, reverse osmosis COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2003-07-22 US disclosed
US-6425944-B2 DURABILITY; ELECTRIC VEHICLES; SPACECRAFT; ION EXCHANGERS; THIN FILMS COMMISSRIAT A L'ENERGIE ATOMIQUE (FR) 2002-07-30 US disclosed
US-6376129-B2 ION EXCHANGE MEMBRANE; POWER SOURCE FOR ELECTRICITY VEHICLES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2002-04-23 US disclosed
US-20010020082-A1 Sulphonated polyimides, membranes prepared with them, and a fuel cell device that includes these membranes FAURE SYLVAIN (FR) 2001-09-06 US disclosed
US-20010019787-A1 Sulphonated polyimides, membranes prepared with them, and a fuel cell device that includes these membranes FAURE SYLVAIN (FR) 2001-09-06 US disclosed