Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 11/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7203695 | 0.88 | LSS (0.56) | LSSACHE | |
| SCHEMBL4804947 | 0.87 | LSS (0.81) | LSSKCNH2ACHE | |
| SCHEMBL4804950 | 0.87 | LSS (0.81) | LSSKCNH2ACHE | |
| SCHEMBL4803247 | 0.83 | LSS (0.92) | LSSACHE | |
| SCHEMBL4803242 | 0.83 | LSS (0.92) | LSSACHE | |
| SCHEMBL4806833 | 0.82 | LSS (0.98) | LSSACHE | |
| SCHEMBL4806835 | 0.82 | LSS (0.98) | LSSACHE | |
| SCHEMBL4800401 | 0.82 | LSS (1.00) | LSSACHE | |
| SCHEMBL4809209 | 0.82 | LSS (0.73) | LSSACHE | |
| SCHEMBL4800389 | 0.82 | LSS (1.00) | LSSACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |