Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 10/20 | 0.56 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | TACR3 | P29371 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202905 | 0.88 | LSS (0.69) | LSSACHE | |
| SCHEMBL7210422 | 0.87 | LSS (0.56) | LSSACHE | |
| SCHEMBL4805082 | 0.85 | LSS (0.68) | LSSACHETACR3LMNAL3MBTL1 | |
| SCHEMBL4805079 | 0.85 | LSS (0.68) | LSSACHETACR3LMNAL3MBTL1 | |
| SCHEMBL4797901 | 0.82 | LSS (0.63) | LSSACHELMNAL3MBTL1 | |
| SCHEMBL4797907 | 0.82 | LSS (0.63) | LSSACHELMNAL3MBTL1 | |
| SCHEMBL4804058 | 0.79 | LSS (0.69) | LSSACHELMNAL3MBTL1 | |
| SCHEMBL4804067 | 0.79 | LSS (0.69) | LSSACHELMNAL3MBTL1 | |
| SCHEMBL4797476 | 0.78 | LSS (0.57) | LSSACHETACR3LMNAL3MBTL1 | |
| SCHEMBL4797473 | 0.78 | LSS (0.57) | LSSACHETACR3LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |