Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27578408 | 0.88 | TSHR (0.47) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL7220330 | 0.78 | TSHR (0.62) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| Trifluoroacetic Acid SCHEMBL6449383 | 0.77 | ITGB3 (0.44) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL11252152 | 0.73 | TSHR (0.58) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL31704435 | 0.73 | TSHR (0.54) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL23292770 | 0.72 | TSHR (0.58) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL23292807 | 0.71 | TSHR (0.56) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL2766162 | 0.71 | KDM4E (0.56) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL23292767 | 0.71 | TSHR (0.56) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL23292793 | 0.71 | TSHR (0.56) | KDM4EUSP2ALDH1A1LMNAMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |