Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.49 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 2/20 | 0.43 |
| ▸ | FNTB | P49356 | 2/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597242 | 0.78 | SLC6A4 (0.43) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL3500166 | 0.75 | CYP11B1 (0.56) | TBXAS1CYP11B1CYP11B2CYP19A1FNTA | |
| Hydrochloric Acid SCHEMBL7983963 | 0.74 | CYP11B1 (0.55) | TBXAS1CYP11B1CYP11B2CYP19A1FNTA | |
| SCHEMBL2356870 | 0.71 | CYP17A1 (0.40) | CYP11B1CYP11B2CYP19A1ADRA2CFNTA | |
| SCHEMBL3501181 | 0.71 | FNTA (0.60) | CYP11B1CYP11B2CYP19A1FNTAFNTB | |
| SCHEMBL1719741 | 0.70 | CYP11B1 (0.72) | NOS1HMOX2CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL2351260 | 0.69 | CYP19A1 (0.39) | CYP11B1CYP11B2CYP19A1ADRA2CFNTA | |
| SCHEMBL10465907 | 0.69 | MRGPRX4 (0.40) | CYP11B1CYP11B2CYP19A1ADRA2CFNTA | |
| SCHEMBL7588280 | 0.68 | TBXAS1 (0.56) | TBXAS1CYP19A1HMOX1 | |
| SCHEMBL688957 | 0.68 | TBXAS1 (0.88) | NOS1HMOX2TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082299-A1 | IMPROVED HORMONE REPLACEMENT THERAPY | JENCAP RESEARCH LTD. (CA) | 2003-10-09 | — | — | WO | disclosed |