Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563131 | 0.90 | MAPT (0.79) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30785795 | 0.90 | MAPT (0.79) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL19909611 | 0.83 | MAPT (0.55) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL22541875 | 0.82 | CYP1A2 (0.62) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL31336201 | 0.80 | MAPT (0.88) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL22534454 | 0.80 | MAPT (0.88) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| 1-Naphthol SCHEMBL5492646 | 0.80 | CYP1A2 (0.74) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL11022631 | 0.80 | TP53 (0.67) | MAPTMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL15400598 | 0.80 | PTPN22 (0.65) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL29027 | 0.80 | PTPN22 (0.65) | MAPTMEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341798-A1 | CHIRAL DIPHOSPHINES AND THEIR METAL COMPLEXES | PPG-Sipsy (FR) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002040492-A1 | CHIRAL DIPHOSPHINES AND THEIR METAL COMPLEXES | PPG-SIPSY (FR) | 2002-05-23 | — | — | WO | disclosed |