Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.79 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CETP | P11597 | 2/20 | 0.50 |
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30785795 | 1.00 | MAPT (0.79) | MAPTHIF1AEPAS1MEN1KMT2A | |
| SCHEMBL7203374 | 0.90 | MAPT (0.62) | MAPTHIF1AMEN1KMT2ANISCH | |
| SCHEMBL998182 | 0.89 | MAPT (1.00) | MAPTMEN1KMT2ANISCHALDH1A1 | |
| SCHEMBL29428410 | 0.89 | MAPT (1.00) | MAPTMEN1KMT2ANISCHALDH1A1 | |
| SCHEMBL31336201 | 0.83 | MAPT (0.88) | MAPTMEN1KMT2ANISCHALDH1A1 | |
| SCHEMBL22534454 | 0.83 | MAPT (0.88) | MAPTMEN1KMT2ANISCHALDH1A1 | |
| SCHEMBL15400598 | 0.82 | PTPN22 (0.65) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL29362162 | 0.82 | PTPN22 (0.65) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL29027 | 0.82 | PTPN22 (0.65) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL31411997 | 0.82 | MAPT (0.57) | MAPTHIF1AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117645525-A | Recovery processing method of pentamethylindane raffinate | 山东新和成药业有限公司 | 2024-03-05 | — | — | CN | claimed |
| EP-0915073-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ISOMERS OF TRICYCLIC COMPOUNDS | TORAY INDUSTRIES (JP) | 2003-08-13 | — | — | EP | claimed |
| CN-117645525-A | Recovery processing method of pentamethylindane raffinate | 山东新和成药业有限公司 | 2024-03-05 | — | — | CN | disclosed |
| US-9687834-B2 | Catalysts for metathesis reactions including enantioselective olefin metathesis, and related methods | TRUSTEES OF BOSTON COLLEGE (US) | 2017-06-27 | — | — | US | disclosed |
| WO-2017090418-A1 | POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME | DIC株式会社 | 2017-06-01 | — | — | WO | disclosed |
| EP-1885732-B1 | CHIRAL DIPHOSPHONITES AS LIGANDS IN THE RUTHENIUM-CATALYSED ENANTIOSELECTIVE REDUCTION OF KETONES ß-KETO-ESTERS AND KETIMINES | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2009-07-22 | — | — | EP | disclosed |
| EP-0992524-B1 | Process for preparing polyether polyols | BAYER AG (DE) | 2004-02-18 | — | — | EP | disclosed |
| US-6624321-B2 | Metathesis ring-opening polymerization of cyclic ethers in the presence of catalysts such as aluminum bis(trifluoromethane-sulfonate) phenolate | BAYER AKTIENGESELLSCHAFT (DE) | 2003-09-23 | — | — | US | disclosed |
| EP-0915073-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ISOMERS OF TRICYCLIC COMPOUNDS | TORAY INDUSTRIES (JP) | 2003-08-13 | — | — | EP | disclosed |
| US-20030097026-A1 | Process for the preparation of polyether polyols | DENNINGER UWE (DE) | 2003-05-22 | — | — | US | disclosed |
| US-6492565-B2 | USING ALKYLENE OXIDE IN PRESENCE OF LEWIS ACID CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-10 | — | — | US | disclosed |
| US-20010053866-A1 | Process for the preparation of polyether polyols | BAYER AKTIENGESELLSCHAFT (DE) | 2001-12-20 | — | — | US | disclosed |
| US-6103914-A | Method of producing optically active material of tricyclic compound | TORAY INDUSTRIES, INC. (JP) | 2000-08-15 | — | — | US | disclosed |
| EP-0992524-A2 | Process for preparing polyether polyols | BAYER AG (DE) | 2000-04-12 | — | — | EP | disclosed |
| US-6020452-A | Chiral biphenyl compounds for use in asymmetric reactions | NORTH DAKOTA STATE UNIVERSITY (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0915073-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ISOMERS OF TRICYCLIC COMPOUNDS | TORAY INDUSTRIES, INC. (JP) | 1999-05-12 | — | — | EP | disclosed |
| US-5889134-A | POLYMER BASED ON A ROTATION-HINDERED 2,2'SUBSTITUTED BIPHENYL SUBUNIT WHICH WHEN REACTED WITH AN ORGANOZINC COMPOUND CATALYZES KETONE REDUCTION BY A BORANE, EPOXIDATION OF AN A,B-UNSATURATED COMPOUND USING OXYGEN; ALDEHYDE ALKYLATION | NORTH DAKOTA STATE UNIVERSITY (US) | 1999-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030097026-A1 | Process for the preparation of polyether polyols | PCBP1, FHIT, PUF60 | MAPT 4187/4885HIF1A 2530/4885EPAS1 2298/4885 |
| US-20010053866-A1 | Process for the preparation of polyether polyols | PCBP1, FHIT, PUF60 | MAPT 4187/4885HIF1A 2530/4885EPAS1 2298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.