Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661621 | 0.80 | TAS1R3 (0.34) | — | |
| SCHEMBL29002059 | 0.71 | SLC1A3 (0.30) | — | |
| SCHEMBL28418458 | 0.70 | TSHR (0.33) | KIF11 | |
| SCHEMBL2987911 | 0.69 | TSHR (0.36) | KIF11 | |
| SCHEMBL11338453 | 0.69 | TSHR (0.36) | KIF11 | |
| SCHEMBL5718396 | 0.69 | TSHR (0.36) | KIF11 | |
| SCHEMBL9619838 | 0.69 | TSHR (0.36) | KIF11 | |
| SCHEMBL5369984 | 0.69 | TSHR (0.36) | KIF11 | |
| SCHEMBL1572815 | 0.69 | TSHR (0.36) | KIF11 | |
| SCHEMBL16568808 | 0.68 | SLC7A5 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586357-B1 | Stereospecific catalysts; enantioselective reduction; transition metal complexes | CHEMI S.P.A. (IT) | 2003-07-01 | — | — | US | disclosed |
| US-6297387-B1 | AND THEIR USE AS CHIRAL CATALYSTS IN STEREOCONTROLLED REACTIONS, SUCH AS DIASTEREO- AND ENANTIOSELECTIVE REDUCTION REACTIONS, | ITALFARMACO SUD S.P.A. (IT) | 2001-10-02 | — | — | US | disclosed |
| US-6133191-A | Heteroaromatic diphosphines as chiral ligands | ITALFARMACO SUD S.P.A. (IT) | 2000-10-17 | — | — | US | disclosed |
| US-6077958-A | Heteroaromatic diphosphines as chiral ligands | ITALFARMACO SUD S.P.A. (IT) | 2000-06-20 | — | — | US | disclosed |
| EP-0770085-B1 | HETEROAROMATIC DIPHOSPHINES AS CHIRAL LIGANDS | CHEMI SPA (IT) | 1999-09-22 | — | — | EP | disclosed |
| US-5907045-A | Heteroaromatic diphosphines as chiral ligands | ITALFARMACO SUD S.P.A. (IT) | 1999-05-25 | — | — | US | disclosed |
| EP-0770085-A1 | HETEROAROMATIC DIPHOSPHINES AS CHIRAL LIGANDS | ITALFARMACO SUD S.p.A. (IT) | 1997-05-02 | — | — | EP | disclosed |
| WO-1996001831-A1 | HETEROAROMATIC DIPHOSPHINES AS CHIRAL LIGANDS | ITALFARMACO SUD S.P.A. (IT) | 1996-01-25 | — | — | WO | disclosed |