Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6593103 | 1.00 | CTSK (0.40) | CTSKPKMDRD4 | |
| SCHEMBL5575176 | 0.94 | CTSK (0.40) | CTSKPKM | |
| SCHEMBL6899315 | 0.92 | CTSK (0.41) | CTSKPKMDRD4 | |
| SCHEMBL4687353 | 0.85 | CTSK (0.52) | CTSKPKMDRD4 | |
| SCHEMBL5096677 | 0.85 | CTSK (0.52) | CTSKPKMDRD4 | |
| SCHEMBL4687256 | 0.82 | CTSK (0.38) | CTSKPKM | |
| SCHEMBL4686550 | 0.82 | CTSK (0.43) | CTSK | |
| SCHEMBL5949076 | 0.77 | CTSK (0.33) | CTSKPKM | |
| SCHEMBL4686403 | 0.77 | CTSK (0.54) | CTSKPKMDRD4 | |
| SCHEMBL4315397 | 0.76 | CTSK (0.38) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229911-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2003-05-07 | — | — | EP | disclosed |
| EP-1229911-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001034153-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |