SCHEMBL7203498

SCHEMBL7203498

CC(C)=[Zr](C1=CC=CC1)(C1c2ccccc2-c2ccccc21)(N(C)C)N(C)C

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.34
SLC22A2 O15244 1/20 0.32
SLC22A3 O75751 1/20 0.32
KMT2A Q03164 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6562418 0.78 POLB (0.33) GPR3POLB
SCHEMBL4443746 0.78 POLB (0.33) GPR3SLC22A2SLC22A3POLB
SCHEMBL8504079 0.72 GPR3 (0.32) GPR3
SCHEMBL6857341 0.72 GPR3 (0.32) GPR3
SCHEMBL6564453 0.71 SLC22A2 (0.30) SLC22A2SLC22A3
SCHEMBL1135085 0.71 SLC22A2 (0.30) SLC22A2SLC22A3
SCHEMBL1135070 0.71
Hydrochloric Acid SCHEMBL18837054 0.71 GPR3 (0.31) GPR3
Fluoride SCHEMBL7640503 0.71 GPR3 (0.31) GPR3
Hydrochloric Acid SCHEMBL565996 0.71 GPR3 (0.31) GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0779306-B1 Process for preparation of cycloolefin copolymers TICONA GMBH (DE) 2003-12-03 EP disclosed
US-6020444-A Process for preparing a cycloolefin copolymer HOECHST AG (DE) 2000-02-01 US disclosed
US-5869586-A USING COORDINATION POLYMERIZATION CATALYST TICONA GMBH (DE) 1999-02-09 US disclosed
EP-0779306-A2 Process for preparation of cycloolefin copolymers HOECHST AKTIENGESELLSCHAFT (DE) 1997-06-18 EP disclosed