Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3065793 | 1.00 | CHRNB2 (0.46) | CHRNB2CHRNA4CHRNA7HRH3HRH1 | |
| Hydrochloric Acid SCHEMBL5698917 | 0.99 | CHRNB2 (0.45) | CHRNB2CHRNA4CHRNA7HRH3HRH1 | |
| Hydrochloric Acid SCHEMBL7204189 | 0.99 | CHRNB2 (0.45) | CHRNB2CHRNA4CHRNA7HRH3HRH1 | |
| Hydrochloric Acid SCHEMBL7204191 | 0.99 | CHRNB2 (0.45) | CHRNB2CHRNA4CHRNA7HRH3HRH1 | |
| Hydrochloric Acid SCHEMBL3075989 | 0.99 | CHRNB2 (0.45) | CHRNB2CHRNA4CHRNA7HRH3HRH1 | |
| Hydrochloric Acid SCHEMBL8481858 | 0.92 | CHRNB2 (0.50) | CHRNB2CHRNA4GAADRD2DRD4 | |
| SCHEMBL7204858 | 0.89 | HRH2 (0.46) | HRH3HRH1GAAHRH2DRD2 | |
| SCHEMBL7204857 | 0.89 | HRH2 (0.46) | HRH3HRH1GAAHRH2DRD2 | |
| Hydrochloric Acid SCHEMBL7205382 | 0.88 | HRH2 (0.45) | HRH3HRH1GAAHRH2DRD2 | |
| Hydrochloric Acid SCHEMBL7205377 | 0.88 | HRH2 (0.45) | HRH3HRH1GAAHRH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003045387-A1 | PHARMACEUTICAL COMPOSITION WITH COMBINED ACTIVE AGENTS CONTAINING METFORMIN AND A HYDROXYLAMINE DERIVATIVE | BIOREX KUTATÓ ÉS FEJLESZTÖ RT. (HU) | 2003-06-05 | — | — | WO | disclosed |