Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 11/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4803161 | 0.88 | LSS (0.71) | LSSLMNA | |
| SCHEMBL4803171 | 0.88 | LSS (0.71) | LSSLMNA | |
| SCHEMBL5069078 | 0.85 | LSS (0.53) | LSSLMNACNR2ALDH1A1MEN1 | |
| SCHEMBL6018787 | 0.84 | LSS (0.80) | LSS | |
| SCHEMBL6018788 | 0.84 | LSS (0.80) | LSS | |
| SCHEMBL6018698 | 0.83 | LSS (0.79) | LSS | |
| SCHEMBL6018693 | 0.83 | LSS (0.79) | LSS | |
| SCHEMBL4796822 | 0.83 | LSS (1.00) | LSS | |
| SCHEMBL4804154 | 0.83 | LSS (1.00) | LSS | |
| SCHEMBL4796825 | 0.83 | LSS (1.00) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |