Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 6/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7203669 | 0.72 | MKNK1 (0.50) | MKNK1CNR2UCHL1FFAR2GSTO1 | |
| SCHEMBL14407987 | 0.69 | CNR2 (0.64) | MKNK1CNR2UCHL1GSTO1USP30 | |
| SCHEMBL14408002 | 0.69 | CNR2 (0.58) | MKNK1CNR2UCHL1GSTO1USP30 | |
| SCHEMBL14408008 | 0.68 | CNR2 (0.59) | MKNK1CNR2UCHL1GSTO1USP30 | |
| SCHEMBL14408007 | 0.68 | CNR2 (0.59) | MKNK1CNR2UCHL1GSTO1USP30 | |
| SCHEMBL14408031 | 0.68 | CKS1B (0.56) | MKNK1CNR2UCHL1FFAR2USP30 | |
| SCHEMBL28014843 | 0.68 | KDR (0.62) | MKNK1UCHL1FFAR2GSTO1USP30 | |
| SCHEMBL20883060 | 0.67 | MKNK1 (0.57) | MKNK1CNR2UCHL1FFAR2GSTO1 | |
| SCHEMBL14408015 | 0.67 | MKNK1 (0.53) | MKNK1CNR2UCHL1PIK3CAGSTO1 | |
| SCHEMBL7203842 | 0.67 | CNR2 (0.53) | MKNK1CNR2UCHL1FFAR2GSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003015778-A1 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2003-02-27 | — | — | WO | disclosed |