Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 10/20 | 0.45 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.45 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5353928 | 0.87 | CNR2 (0.59) | CNR2MKNK1NPY5RUSP30UCHL1 | |
| SCHEMBL14408005 | 0.82 | CNR2 (0.62) | CNR2MKNK1NPY5RUSP30UCHL1 | |
| SCHEMBL14408031 | 0.81 | CKS1B (0.56) | CNR2MKNK1NPY5RUSP30UCHL1 | |
| SCHEMBL5349433 | 0.80 | CNR2 (0.62) | CNR2MKNK1NPY5RUSP30FFAR2 | |
| SCHEMBL14332861 | 0.79 | GPR119 (0.48) | MKNK1USP30 | |
| SCHEMBL14407987 | 0.78 | CNR2 (0.64) | CNR2MKNK1NPY5RUSP30UCHL1 | |
| SCHEMBL28497363 | 0.76 | MKNK1 (0.67) | CNR2MKNK1USP30UCHL1 | |
| SCHEMBL19296045 | 0.76 | MKNK1 (0.67) | CNR2MKNK1USP30UCHL1 | |
| SCHEMBL14333281 | 0.76 | MKNK1 (0.46) | CNR2MKNK1NPY5RUSP30UCHL1 | |
| SCHEMBL14332817 | 0.76 | MKNK1 (0.48) | CNR2MKNK1NPY5RUSP30UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003015778-A1 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2003-02-27 | — | — | WO | disclosed |