Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LSS | P48449 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7203967 | 1.00 | USP30 (0.45) | USP30RAB9ALSSPOLBKCNH2 | |
| SCHEMBL7206026 | 0.90 | LSS (0.48) | RAB9ALSS | |
| SCHEMBL7209755 | 0.90 | LSS (0.48) | RAB9ALSS | |
| SCHEMBL7208575 | 0.90 | LSS (0.48) | RAB9ALSS | |
| SCHEMBL7209758 | 0.90 | LSS (0.48) | RAB9ALSS | |
| SCHEMBL7208569 | 0.90 | LSS (0.48) | RAB9ALSS | |
| SCHEMBL7206024 | 0.90 | LSS (0.48) | RAB9ALSS | |
| SCHEMBL7208470 | 0.89 | LSS (0.47) | RAB9ALSS | |
| SCHEMBL7208465 | 0.89 | LSS (0.47) | RAB9ALSS | |
| SCHEMBL7208600 | 0.89 | LMNA (0.41) | LSSKCNH2GPR119EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |