SCHEMBL7204038

SCHEMBL7204038

CCCCCCCCc1ccc(N)c(N)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SKP2 Q13309 1/20 0.61
HTR2A P28223 1/20 0.57
PTGS2 P35354 3/20 0.52
ESR1 P03372 2/20 0.52
ADRA2A P08913 2/20 0.52
ADORA3 P0DMS8 2/20 0.52
TACR2 P21452 2/20 0.52
SLC6A2 P23975 2/20 0.52
SLC6A4 P31645 2/20 0.52
SLC6A3 Q01959 2/20 0.52
KDM4E B2RXH2 2/20 0.52
ALDH1A1 P00352 2/20 0.52
HSD17B10 Q99714 2/20 0.52
LMNA P02545 1/20 0.52
SHBG P04278 1/20 0.52
TP53 P04637 1/20 0.52
CYP3A4 P08684 1/20 0.52
HSPD1 P10809 1/20 0.52
ADRB3 P13945 1/20 0.52
HTR2C P28335 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11322552 1.00 SKP2 (0.61) SKP2HTR2APTGS2ESR1ADRA2A
SCHEMBL25433778 1.00 SKP2 (0.61) SKP2HTR2APTGS2ESR1ADRA2A
SCHEMBL6348569 1.00 SKP2 (0.61) SKP2HTR2APTGS2ESR1ADRA2A
SCHEMBL10752071 0.98 SKP2 (0.63) SKP2HTR2APTGS2ESR1ADRA2A
SCHEMBL29511379 0.92 SKP2 (0.71) SKP2HTR2APTGS2ESR1ADRA2A
SCHEMBL7204931 0.92 SKP2 (0.71) SKP2HTR2APTGS2ESR1ADRA2A
SCHEMBL30439206 0.85 SKP2 (0.58) SKP2HTR2APTGS2ESR1ADRA2A
SCHEMBL11869178 0.85 SKP2 (0.86) SKP2HTR2APTGS2ESR1ADRA2A
SCHEMBL10623217 0.85 SKP2 (0.58) SKP2HTR2APTGS2ESR1ADRA2A
SCHEMBL5830877 0.85 HTR2A (0.53) SKP2HTR2APTGS2ESR1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0622359-B1 Quinoxaline compound, liquid crystal composition containing the compound, liquid crystal device using the composition, display apparatus and display method CANON KK (JP) 2003-03-19 EP disclosed
US-5512209-A IMPROVED RESPONSE CHARACTERISTICS AND HIGH CONTRAST; DISPOSING COMPOSITION BETWEEN ELECTRODE PLATES CANON KABUSHIKI KAISHA (JP) 1996-04-30 US disclosed
EP-0622359-A1 Quinoxaline compound, liquid crystal composition containing the compound, liquid crystal device using the composition, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1994-11-02 EP disclosed