Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29511379 | 1.00 | SKP2 (0.71) | SKP2CA2SMN1; SMN2HPGDNPC1 | |
| SCHEMBL10752071 | 0.94 | SKP2 (0.63) | SKP2CA2SMN1; SMN2HPGDRAB9A | |
| SCHEMBL6348569 | 0.92 | SKP2 (0.61) | SKP2SMN1; SMN2HPGDRAB9AHTR2A | |
| SCHEMBL7204038 | 0.92 | SKP2 (0.61) | SKP2SMN1; SMN2HPGDRAB9AHTR2A | |
| SCHEMBL11322552 | 0.92 | SKP2 (0.61) | SKP2SMN1; SMN2HPGDRAB9AHTR2A | |
| SCHEMBL25433778 | 0.92 | SKP2 (0.61) | SKP2SMN1; SMN2HPGDRAB9AHTR2A | |
| SCHEMBL5604961 | 0.86 | SKP2 (0.53) | SKP2CA2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL13896981 | 0.85 | SKP2 (0.69) | SKP2CA2SMN1; SMN2HPGDNPC1 | |
| SCHEMBL3546545 | 0.84 | SKP2 (0.58) | SKP2CA2SMN1; SMN2HPGDNPC1 | |
| SCHEMBL28995075 | 0.84 | SKP2 (0.53) | SKP2SMN1; SMN2HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108689860-A | A kind of synthetic method preparing 4- butyl benzene -1,2- diamines | 荆门医药工业技术研究院 | 2018-10-23 | — | — | CN | claimed |
| EP-0292176-A2 | Organo-metal compositions, preparation and use | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-11-23 | — | — | EP | claimed |
| CN-114436972-B | Pabendazole derivative, and preparation method and application thereof | 山东大学 | 2024-02-13 | — | — | CN | disclosed |
| WO-2023239007-A1 | BENZIMIDAZOLE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER OR INFECTIOUS DISEASES CONTAINING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2023-12-14 | — | — | WO | disclosed |
| WO-2023239007-A1 | BENZIMIDAZOLE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER OR INFECTIOUS DISEASES CONTAINING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2023-12-14 | — | — | WO | disclosed |
| CN-114436972-A | Pabendazole derivative and preparation method and application thereof | 山东大学 | 2022-05-06 | — | — | CN | disclosed |
| CN-108572228-B | HPLC (high performance liquid chromatography) determination method for 5-butyl benzotriazole and impurities thereof | 荆门医药工业技术研究院 | 2020-08-25 | — | — | CN | disclosed |
| CN-107954939-B | N under a kind of microwave radiation, the method for the thio formyl chloride derivatives catalysis synthesizing benzimidazole derivative of N- dimethylamino | 福建医科大学 | 2019-09-17 | — | — | CN | disclosed |
| CN-109180590-A | A method of Benzoheterocyclic compounds are quickly prepared using physical grinding method under room temperature solvent-free | 福建医科大学 | 2019-01-11 | — | — | CN | disclosed |
| CN-108689860-A | A kind of synthetic method preparing 4- butyl benzene -1,2- diamines | 荆门医药工业技术研究院 | 2018-10-23 | — | — | CN | disclosed |
| CN-108689860-A | A kind of synthetic method preparing 4- butyl benzene -1,2- diamines | 荆门医药工业技术研究院 | 2018-10-23 | — | — | CN | disclosed |
| EP-0042753-A1 | Nonapeptide and decapeptide agonists of luteinizing hormone releasing hormone containing heterocyclic amino acid residues, methods for their preparation, pharmaceutical compounds containing them, and their pharmaceutical use | SYNTEX (U.S.A.) INC. (US) | 1981-12-30 | — | — | EP | disclosed |
| US-4285878-A | N-Phenyl-N'-cyano-O-phenylisoureas | SMITHKLINE CORPORATION (US) | 1981-08-25 | — | — | US | disclosed |
| EP-0000574-A1 | Benzimidazole-2 derivatives, their preparation and their use for the preparation of medicaments | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | disclosed |
| US-4137310-A | LARVICIDES | AMERICAN CYANAMID COMPANY (US) | 1979-01-30 | — | — | US | disclosed |
| US-4123536-A | Dialkyl ({[3-(alkoxycarbonyl)-1,4-dihydro-4-oxo-8-quinolinyl]amino}methylene)propanedioates | WARNER-LAMBERT COMPANY (US) | 1978-10-31 | — | — | US | disclosed |
| US-4060491-A | 5-ALKYL BENZOTRIAZOLE | MOBIL OIL CORPORATION (US) | 1977-11-29 | — | — | US | disclosed |
| US-3965092-A | HEAT EXCHANGE, SURFACTANTS | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1976-06-22 | — | — | US | disclosed |
| US-3953452-A | Perinone dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-27 | — | — | US | disclosed |
| US-3950391-A | FUNGICIDES, MITICIDES, OVICIDES | ADAMS CHARLES D | 1976-04-13 | — | — | US | disclosed |