Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6341433 | 1.00 | ALDH1A1 (0.44) | ALDH1A1NPSR1PREPKMT2AMEN1 | |
| SCHEMBL6333422 | 0.83 | PARP1 (0.47) | KMT2AMEN1CRHBPCRHR2BCHE | |
| SCHEMBL6336995 | 0.83 | PARP1 (0.47) | KMT2AMEN1CRHBPCRHR2BCHE | |
| SCHEMBL6635272 | 0.79 | PARP1 (0.45) | KMT2AMEN1CRHBPCRHR2 | |
| SCHEMBL7006162 | 0.77 | KMT2A (0.45) | KMT2AMEN1CRHBPCRHR2BCHE | |
| SCHEMBL18506016 | 0.76 | PREP (0.52) | NPSR1PREPTSHRL3MBTL1ACE2 | |
| SCHEMBL6540897 | 0.76 | MEN1 (0.46) | KMT2AMEN1CRHBPCRHR2BCHE | |
| SCHEMBL6906741 | 0.75 | MEN1 (0.41) | KMT2AMEN1CRHBPCRHR2BCHE | |
| SCHEMBL6337611 | 0.75 | KDM4E (0.55) | ALDH1A1NPSR1PREPKMT2AMEN1 | |
| SCHEMBL6541558 | 0.73 | ALDH1A1 (0.39) | ALDH1A1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294700-A2 | BENZHYDRYL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000631-A2 | BENZHYDRYL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |