SCHEMBL7204251

SCHEMBL7204251

CCOC(C)COS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.40
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40
STAT3 P40763 1/20 0.39
ALDH1A1 P00352 5/20 0.39
GAA P10253 3/20 0.38
GBA1 P04062 1/20 0.37
KMT2A Q03164 4/20 0.37
BCHE P06276 1/20 0.37
ACHE P22303 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
MEN1 O00255 1/20 0.37
LMNA P02545 2/20 0.36
DHODH Q02127 1/20 0.36
VDR P11473 1/20 0.36
TSHR P16473 1/20 0.36
CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9261226 0.88 CA12 (0.41) CA2CA12CA9STAT3ALDH1A1
SCHEMBL7809011 0.86 CA9 (0.45) CA2CA12CA9STAT3ALDH1A1
SCHEMBL23160909 0.86 CA9 (0.45) CA2CA12CA9STAT3ALDH1A1
SCHEMBL21618245 0.85 VDR (0.41) CA2CA12CA9STAT3ALDH1A1
SCHEMBL9723867 0.85 CA12 (0.40) CA2CA12CA9STAT3ALDH1A1
SCHEMBL9512685 0.85 CA12 (0.40) CA2CA12CA9STAT3ALDH1A1
SCHEMBL21114440 0.85 GAA (0.42) CA2CA12CA9STAT3ALDH1A1
SCHEMBL21114539 0.85 GAA (0.42) CA2CA12CA9STAT3ALDH1A1
SCHEMBL21114486 0.85 GAA (0.42) CA2CA12CA9STAT3ALDH1A1
SCHEMBL21114439 0.85 GAA (0.42) CA2CA12CA9STAT3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115020810-A Electrolyte and application thereof 湖北亿纬动力有限公司 2022-09-06 CN disclosed
EP-1035123-B1 NOVEL HETEROCYCLIC COMPOUNDS SUMITOMO PHARMA (JP) 2003-08-20 EP disclosed
US-6329381-B1 INTERFERONS, VIRICIDES AND ANTICARCINOGENIC AGENTS SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2001-12-11 US disclosed
EP-1035123-A1 NOVEL HETEROCYCLIC COMPOUNDS SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2000-09-13 EP disclosed
EP-0319482-B1 Novel substituted propane phosphinic acid compounds CIBA GEIGY AG (CH) 1994-05-18 EP disclosed
US-5300679-A Antagonists to 4-aminobutyric acid CIBA-GEIGY CORPORATION (US) 1994-04-05 US disclosed
US-5190933-A Treatment of cognitive and memory disorders CIBA-GEIGY CORPORATION (US) 1993-03-02 US disclosed
US-5064819-A Antidepressants, anxiolytic agents, GABA antagonists CIBA-GEIGY CORPORATION (US) 1991-11-12 US disclosed
US-5051524-A Treatment of a phosphinic acid with an anhydrous protic medium CIBA-GEIGY CORPORATION (US) 1991-09-24 US disclosed
US-5013863-A Learning enhancement CIBA-GEIGY CORPORATION (US) 1991-05-07 US disclosed
US-4880560-A ENANTIOMORPHS, PHENYL OR BIPHENYL CARBOXYLIC ACID CANON KABUSHIKI KAISHA (JP) 1989-11-14 US disclosed
EP-0319479-A2 Substituted propane-phosphinic acid compounds CIBA-GEIGY AG (CH) 1989-06-07 EP disclosed
EP-0319482-A2 Novel substituted propane phosphinic acid compounds CIBA-GEIGY AG (CH) 1989-06-07 EP disclosed
US-4812259-A POLARIZATION, FERROELECTRICITY CANON KABUSHIKI KAISHA (JP) 1989-03-14 US disclosed