SCHEMBL7204289

SCHEMBL7204289

CC(C)(C)c1cc(Oc2ccc(O)c(C(C)(C)C)c2)ccc1O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESRRA P11474 6/20 0.72
ALDH1A1 P00352 4/20 0.62
ALOX15 P16050 2/20 0.59
NR1I2 O75469 1/20 0.59
LMNA P02545 1/20 0.59
CYP2C9 P11712 1/20 0.59
MIF P14174 1/20 0.59
TYR P14679 1/20 0.59
HTT P42858 1/20 0.59
NFE2L2 Q16236 1/20 0.59
HSD17B10 Q99714 1/20 0.59
GAA P10253 2/20 0.56
NR1H4 Q96RI1 4/20 0.53
ATM Q13315 2/20 0.53
MAPT P10636 2/20 0.52
KDM4E B2RXH2 1/20 0.52
CYP1A2 P05177 1/20 0.52
ATP2A2 P16615 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
ATP2A3 Q93084 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12323552 0.89 ESRRA (0.65) ESRRAALDH1A1ALOX15NR1I2LMNA
SCHEMBL9008266 0.88 ESRRA (0.59) ESRRAALDH1A1ALOX15NR1I2LMNA
SCHEMBL8632740 0.86 ESRRA (0.61) ESRRAALDH1A1ALOX15NR1I2LMNA
SCHEMBL35535 0.85 ALDH1A1 (0.73) ESRRAALDH1A1ALOX15NR1I2LMNA
SCHEMBL29362042 0.85 ALDH1A1 (0.73) ESRRAALDH1A1ALOX15NR1I2LMNA
SCHEMBL6142004 0.85 ALDH1A1 (0.73) ESRRAALDH1A1ALOX15NR1I2LMNA
SCHEMBL11347106 0.85 ESRRA (0.78) ESRRAALDH1A1NR1H4ATMMAPT
SCHEMBL15511820 0.84 ESRRA (0.55) ESRRAALDH1A1ALOX15NR1I2LMNA
SCHEMBL20548778 0.83 ALDH1A1 (0.71) ESRRAALDH1A1ALOX15NR1I2LMNA
SCHEMBL10595513 0.83 ALDH1A1 (0.59) ESRRAALDH1A1ALOX15NR1I2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104968704-B Process for producing polyarylate 三菱瓦斯化学株式会社 2016-12-14 CN disclosed
CN-104968704-A Process for producing polyarylate MITSUBISHI GAS CHEMICAL CO 2015-10-07 CN disclosed
US-6603035-B1 A method for producing a high purity cyanate comprising reacting a phenol compound represented by the following formula SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-08-05 US disclosed