Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3257641 | 0.80 | TSHR (0.33) | — | |
| SCHEMBL22292128 | 0.78 | — | — | |
| SCHEMBL5066889 | 0.75 | MGAM (0.38) | MAPT | |
| SCHEMBL17818836 | 0.75 | SMN1; SMN2 (0.36) | KDM4EMAPTAPOBEC3G | |
| SCHEMBL10207770 | 0.74 | GAA (0.41) | KDM4E | |
| SCHEMBL1018739 | 0.72 | — | — | |
| SCHEMBL24812030 | 0.71 | GRIN2D (0.36) | — | |
| SCHEMBL14146256 | 0.70 | ALDH1A1 (0.38) | — | |
| SCHEMBL7226727 | 0.69 | — | — | |
| SCHEMBL712145 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240442-B1 | PREPARATION PROCESS USEFUL IN SYNTHESIS OF ATORVASTATIN | MEDICHEM KOREA CO LTD (KR) | 2012-06-20 | — | — | EP | disclosed |
| US-8124790-B2 | Preparation process useful in synthesis of atorvastatin | MEDICHEM KOREA CO., LTD. (KR) | 2012-02-28 | — | — | US | disclosed |
| US-20110112309-A1 | PREPARATION PROCESS USEFUL IN SYNTHESIS OF ATORVASTATIN | MEDICHEM KOREA CO., LTD. (KR) | 2011-05-12 | — | — | US | disclosed |
| EP-2240442-A2 | PREPARATION PROCESS USEFUL IN SYNTHESIS OF ATORVASTATIN | Medichem Korea. Co., Ltd. (KR) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009084773-A2 | PREPARATION PROCESS USEFUL IN SYNTHESIS OF ATORVASTATIN | MEDICHEM KOREA. CO., LTD. (KR) | 2009-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112309-A1 | PREPARATION PROCESS USEFUL IN SYNTHESIS OF ATORVASTATIN | HMGCR, DHCR7, LIPA | KDM4E 1306/4885MAPT 3642/4885APOBEC3G 2091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.