SCHEMBL7204305

SCHEMBL7204305

CCCCOc1ccccc1C(C)(C)C1=C([Ti])CC=C1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.40
CYP2C19 P33261 4/20 0.40
CYP2C9 P11712 2/20 0.40
ALDH1A1 P00352 7/20 0.38
KDM4E B2RXH2 3/20 0.37
CYP2D6 P10635 2/20 0.36
HSD17B10 Q99714 1/20 0.36
L3MBTL1 Q9Y468 6/20 0.34
TSHR P16473 2/20 0.34
MAPT P10636 3/20 0.33
NPSR1 Q6W5P4 2/20 0.33
CSNK1A1 P48729 1/20 0.33
CSNK1D P48730 1/20 0.33
PRKCD Q05655 1/20 0.33
PAK1 Q13153 1/20 0.33
CAMK2B Q13554 1/20 0.33
CAMK2G Q13555 1/20 0.33
CAMK2D Q13557 1/20 0.33
TAOK1 Q7L7X3 1/20 0.33
CYP19A1 P11511 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6338574 0.88 HTR2A (0.36) CYP1A2CYP2C19ALDH1A1CYP2D6HSD17B10
SCHEMBL7200121 0.81
Hydrochloric Acid SCHEMBL6340584 0.80
Hydrochloric Acid SCHEMBL6332586 0.80 CA1 (0.34) ALDH1A1TSHRMAPTNPSR1GAA
Hydrochloric Acid SCHEMBL6330160 0.77 CYP1A2 (0.36) CYP1A2CYP2C19CYP2C9ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL6332922 0.76
SCHEMBL10787315 0.72 ALDH1A1 (0.58) CYP1A2CYP2C19CYP2C9ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL6338571 0.72 ALDH1A1 (0.36) CYP1A2CYP2C19ALDH1A1KDM4ECYP2D6
SCHEMBL9579880 0.70 CYP1A2 (0.53) CYP1A2CYP2C19CYP2C9ALDH1A1KDM4E
SCHEMBL11133824 0.68 ALDH1A1 (0.60) CYP1A2CYP2C19CYP2C9ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030171212-A1 Transition metal compound, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2003-09-11 US disclosed