Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | FERMT2 | Q96AC1 | 3/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.37 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| M-Xylene SCHEMBL27982228 | 0.86 | SYK (0.50) | CXCR4SCN9AKCNH2SCN5AZAP70 | |
| SCHEMBL11480039 | 0.83 | SCN9A (0.44) | CXCR4SCN9AHRH4ALDH1A1KCNH2 | |
| SCHEMBL28899507 | 0.80 | TLR8 (0.57) | SCN9AHRH3HRH4 | |
| SCHEMBL13034199 | 0.79 | CXCR4 (0.54) | CXCR4FERMT2ALDH1A1ZAP70SYK | |
| SCHEMBL8133400 | 0.79 | CXCR4 (0.54) | CXCR4HRH3FERMT2HRH4ALDH1A1 | |
| SCHEMBL19477216 | 0.79 | MKNK1 (0.50) | SCN9AALDH1A1KCNH2SCN5A | |
| SCHEMBL10188245 | 0.79 | HRH4 (0.48) | CXCR4SCN9AHRH3HRH4KCNH2 | |
| SCHEMBL11404764 | 0.78 | PDPK1 (0.50) | SCN9AHRH4KCNH2SCN5A | |
| SCHEMBL15748924 | 0.78 | SCN9A (0.40) | CXCR4SCN9AHRH4KCNH2SCN5A | |
| SCHEMBL15651573 | 0.78 | HTR7 (0.56) | HRH3HRH4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921122-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-05-21 | — | — | EP | disclosed |
| US-6110967-A | USEFUL AS AGENTS FOR PREVENTING AND TREATING METABOLIC OSTEOPATHY SUCH AS OSTEOPOROSIS, HYPERCALCEMIA AND BONE METASTASIS OF CANCER BECAUSE THEY SPECIFICALLY INHIBITS CATHEPSIN L AND ITS FAMILY ENZYMES TO INHIBIT BONE RESORPTION | TAIHO PHARMACEUTICALS CO., LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-0921122-A1 | NOVEL EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1999-06-09 | — | — | EP | disclosed |