Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 6/20 | 0.39 |
| ▸ | PDE4A | P27815 | 4/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4858290 | 0.81 | ATM (0.65) | ATMCYP19A1GRM1PDE4APDE4B | |
| SCHEMBL31695293 | 0.78 | ATM (0.71) | ATMCYP19A1GRM1PDE4APDE4B | |
| SCHEMBL29353750 | 0.77 | ATM (0.65) | ATMCYP19A1GRM1PDE4APDE4B | |
| SCHEMBL641536 | 0.77 | ATM (0.65) | ATMCYP19A1GRM1PDE4APDE4B | |
| SCHEMBL2623615 | 0.74 | ATM (0.56) | ATMCYP19A1GRM1 | |
| SCHEMBL8861152 | 0.74 | ATM (0.56) | ATMCYP19A1GRM1 | |
| SCHEMBL15219695 | 0.74 | ATM (0.56) | ATMCYP19A1GRM1 | |
| SCHEMBL3073477 | 0.74 | ATM (0.59) | ATMCYP19A1GRM1EPHX2POLB | |
| SCHEMBL8606849 | 0.73 | ATM (0.47) | ATMCYP19A1GRM1PDE4APDE4B | |
| SCHEMBL20636604 | 0.72 | ATM (0.54) | ATMCYP19A1GRM1PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892805-B1 | PRODUCTION OF 7-AMINOCEPHALOSPORANIC ACID DERIVATIVE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-07-02 | — | — | EP | disclosed |
| EP-0892805-A1 | PRODUCTION OF 7-AMINOCEPHALOSPORANIC ACID DERIVATIVE | Takeda Chemical Industries, Ltd. (JP) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997039002-A1 | PRODUCTION OF 7-AMINOCEPHALOSPORANIC ACID DERIVATIVE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-23 | — | — | WO | disclosed |
| EP-0229369-A2 | Cephalosporins, process for their preparation and pharmaceutical compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1987-07-22 | — | — | EP | disclosed |
| EP-0225634-A2 | Antibacterial compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-06-16 | — | — | EP | disclosed |
| EP-0203271-A2 | Antibacterial compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-12-03 | — | — | EP | disclosed |
| EP-0164122-A2 | Cephem compounds | Takeda Chemical Industries, Ltd. (JP) | 1985-12-11 | — | — | EP | disclosed |
| EP-0164113-A2 | 3-pyrazolo(1,5-a)pyridinium cephem compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-12-11 | — | — | EP | disclosed |
| EP-0160252-A2 | Antibacterial compounds | Takeda Chemical Industries, Ltd. (JP) | 1985-11-06 | — | — | EP | disclosed |