Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.60 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.58 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.58 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | CCND2 | P30279 | 1/20 | 0.46 |
| ▸ | CCND3 | P30281 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211527 | 0.86 | ADORA2A (0.62) | ADORA2AADORA1ADORA2BTMIGD3TLR7 | |
| SCHEMBL7208425 | 0.86 | ADORA2A (0.76) | ADORA2AADORA1ADORA2BTMIGD3TLR7 | |
| SCHEMBL7206373 | 0.85 | L3MBTL1 (0.47) | ADORA2AADORA1ADORA2BTMIGD3CDK4 | |
| SCHEMBL7205425 | 0.84 | ADORA2A (0.69) | ADORA2AADORA1ADORA2BTMIGD3TLR7 | |
| SCHEMBL7204596 | 0.83 | ADORA1 (0.78) | ADORA2AADORA1ADORA2BTMIGD3TLR7 | |
| SCHEMBL7210269 | 0.83 | ADORA2A (0.58) | ADORA2AADORA1ADORA2BTMIGD3TLR7 | |
| SCHEMBL2060202 | 0.82 | ADORA2A (0.63) | ADORA2AADORA1ADORA2BTMIGD3ALDH1A1 | |
| SCHEMBL7210294 | 0.82 | ADORA2A (0.72) | ADORA2AADORA1ADORA2BTMIGD3TLR7 | |
| SCHEMBL7206049 | 0.81 | ADORA2A (0.68) | ADORA2AADORA1ADORA2BTMIGD3TLR7 | |
| SCHEMBL7210333 | 0.81 | ADORA2A (0.62) | ADORA2AADORA1ADORA2BTMIGD3TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035123-B1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMA (JP) | 2003-08-20 | — | — | EP | disclosed |
| US-6329381-B1 | INTERFERONS, VIRICIDES AND ANTICARCINOGENIC AGENTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1035123-A1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-09-13 | — | — | EP | disclosed |