Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.61 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7204601 | 0.89 | ADORA2A (0.60) | ADORA2AADORA1TMIGD3ADORA2BTLR7 | |
| SCHEMBL7205536 | 0.85 | TLR7 (0.44) | ADORA2AADORA1TLR7KDM4EALDH1A1 | |
| SCHEMBL5732024 | 0.83 | ADORA2A (0.65) | ADORA2AADORA1TMIGD3ADORA2BTLR7 | |
| SCHEMBL7206049 | 0.82 | ADORA2A (0.68) | ADORA2AADORA1TMIGD3ADORA2BTLR7 | |
| SCHEMBL2913215 | 0.81 | ADORA2A (0.67) | ADORA2AADORA1TMIGD3ADORA2BTLR7 | |
| SCHEMBL7210266 | 0.80 | ADORA2A (0.61) | ADORA2AADORA1TMIGD3ADORA2BTLR7 | |
| SCHEMBL7205701 | 0.80 | ADORA2A (0.61) | ADORA2AADORA1TMIGD3ADORA2BTLR7 | |
| SCHEMBL7211527 | 0.80 | ADORA2A (0.62) | ADORA2AADORA1TMIGD3ADORA2BTLR7 | |
| SCHEMBL20343824 | 0.79 | ADORA2A (0.60) | ADORA2AADORA1TMIGD3ADORA2BTLR7 | |
| SCHEMBL3146728 | 0.78 | ADORA2A (0.62) | ADORA2AADORA1TMIGD3ADORA2BTLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035123-B1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMA (JP) | 2003-08-20 | — | — | EP | disclosed |
| US-6329381-B1 | INTERFERONS, VIRICIDES AND ANTICARCINOGENIC AGENTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1035123-A1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-09-13 | — | — | EP | disclosed |